Postinjury hyperfibrinogenemia compromises efficacy of heparin-based venous thromboembolism prophylaxis.

Harr, Jeffrey N; Moore, Ernest E; Chin, Theresa L; Ghasabyan, Arsen; Gonzalez, Eduardo; Wohlauer, Max V; Sauaia, Angela; Banerjee, Anirban; Silliman, Christopher C

Harr, Jeffrey N; Moore, Ernest E; Chin, Theresa L; Ghasabyan, Arsen; Gonzalez, Eduardo; Wohlauer, Max V; Sauaia, Angela; Banerjee, Anirban; Silliman, Christopher C.

Affiliation

Harr JN; *Department of Surgery, University of Colorado Denver, Aurora; Department of Surgery, Denver Health Medical Center, Denver; Trauma Research Center and §Department of Pediatrics, University of Colorado Denver, Aurora; and â¥Research Department, Bonfils Blood Center, Denver, Colorado.

Shock ; 41(1): 33-9, 2014 Jan.

Article in En | MEDLINE | ID: mdl-24351527

Subject(s)

Anticoagulants/therapeutic use; Fibrinogen/metabolism; Heparin, Low-Molecular-Weight/therapeutic use; Venous Thromboembolism/etiology; Venous Thromboembolism/prevention & control; Wounds and Injuries/complications; Adolescent; Adult; Aged; Anticoagulants/administration & dosage; Anticoagulants/antagonists & inhibitors; Blood Coagulation/drug effects; Dose-Response Relationship, Drug; Female; Fibrinogen/pharmacology; Heparin, Low-Molecular-Weight/administration & dosage; Heparin, Low-Molecular-Weight/antagonists & inhibitors; Humans; Injury Severity Score; Male; Middle Aged; Thrombelastography/methods; Treatment Outcome; Venous Thromboembolism/blood; Wounds and Injuries/blood; Young Adult

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Wounds and Injuries / Fibrinogen / Heparin, Low-Molecular-Weight / Venous Thromboembolism / Anticoagulants Type of study: Clinical_trials / Guideline Limits: Adolescent / Adult / Aged / Female / Humans / Male / Middle aged Language: En Journal: Shock Journal subject: ANGIOLOGIA / CARDIOLOGIA Year: 2014 Type: Article

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