The crystal structure of the streptococcal collagen-like protein 2 globular domain from invasive M3-type group A Streptococcus shows significant similarity to immunomodulatory HIV protein gp41.

Squeglia, Flavia; Bachert, Beth; De Simone, Alfonso; Lukomski, Slawomir; Berisio, Rita

Squeglia, Flavia; Bachert, Beth; De Simone, Alfonso; Lukomski, Slawomir; Berisio, Rita.

Affiliation

Squeglia F; From the Institute of Biostructures and Bioimaging, Consiglio Nazionale delle Ricerche, Via Mezzocannone 16, I-80134 Napoli, Italy.

J Biol Chem ; 289(8): 5122-33, 2014 Feb 21.

Article in En | MEDLINE | ID: mdl-24356966

Subject(s)

Bacterial Proteins/chemistry; Collagen/chemistry; HIV Envelope Protein gp41/chemistry; Immunologic Factors/chemistry; Streptococcus pyogenes/metabolism; Structural Homology, Protein; Amino Acid Sequence; Bacterial Proteins/metabolism; Collagen/metabolism; Crystallography, X-Ray; Humans; Molecular Dynamics Simulation; Molecular Sequence Data; Protein Structure, Secondary; Protein Structure, Tertiary; Sequence Alignment; Solutions

Key words

Collagen; Crystal Structure; Molecular Dynamics; Protein Folding; Streptococcus

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Streptococcus pyogenes / Bacterial Proteins / HIV Envelope Protein gp41 / Collagen / Structural Homology, Protein / Immunologic Factors Type of study: Prognostic_studies Limits: Humans Language: En Journal: J Biol Chem Year: 2014 Type: Article Affiliation country: Italy

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