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Integrated phenotypic and activity-based profiling links Ces3 to obesity and diabetes.
Dominguez, Eduardo; Galmozzi, Andrea; Chang, Jae Won; Hsu, Ku-Lung; Pawlak, Joanna; Li, Weiwei; Godio, Cristina; Thomas, Jason; Partida, David; Niessen, Sherry; O'Brien, Paul E; Russell, Aaron P; Watt, Matthew J; Nomura, Daniel K; Cravatt, Benjamin F; Saez, Enrique.
Affiliation
  • Dominguez E; Department of Chemical Physiology and The Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, California, USA.
  • Galmozzi A; Department of Chemical Physiology and The Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, California, USA.
  • Chang JW; Department of Chemical Physiology and The Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, California, USA.
  • Hsu KL; Department of Chemical Physiology and The Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, California, USA.
  • Pawlak J; Department of Chemical Physiology and The Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, California, USA.
  • Li W; Department of Chemical Physiology and The Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, California, USA.
  • Godio C; Department of Chemical Physiology and The Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, California, USA.
  • Thomas J; Department of Chemical Physiology and The Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, California, USA.
  • Partida D; Department of Chemical Physiology and The Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, California, USA.
  • Niessen S; Department of Chemical Physiology and The Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, California, USA.
  • O'Brien PE; Centre for Obesity Research and Education-Monash University, The Alfred Hospital, Prahran, Australia.
  • Russell AP; Centre for Physical Activity and Nutrition Research School of Exercise and Nutrition Sciences, Deakin University, Burwood, Australia.
  • Watt MJ; Biology of Lipid Metabolism Laboratory, Department of Physiology, Monash University, Clayton, Victoria, Australia.
  • Nomura DK; Department of Chemical Physiology and The Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, California, USA.
  • Cravatt BF; Department of Chemical Physiology and The Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, California, USA.
  • Saez E; Department of Chemical Physiology and The Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, California, USA.
Nat Chem Biol ; 10(2): 113-21, 2014 Feb.
Article in En | MEDLINE | ID: mdl-24362705
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Phenotype / Carboxylic Ester Hydrolases / Diabetes Mellitus / Small Molecule Libraries / Obesity Limits: Animals Language: En Journal: Nat Chem Biol Journal subject: BIOLOGIA / QUIMICA Year: 2014 Type: Article Affiliation country: United States
Fulltext
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Phenotype / Carboxylic Ester Hydrolases / Diabetes Mellitus / Small Molecule Libraries / Obesity Limits: Animals Language: En Journal: Nat Chem Biol Journal subject: BIOLOGIA / QUIMICA Year: 2014 Type: Article Affiliation country: United States