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Repurposing diflunisal for familial amyloid polyneuropathy: a randomized clinical trial.
Berk, John L; Suhr, Ole B; Obici, Laura; Sekijima, Yoshiki; Zeldenrust, Steven R; Yamashita, Taro; Heneghan, Michael A; Gorevic, Peter D; Litchy, William J; Wiesman, Janice F; Nordh, Erik; Corato, Manuel; Lozza, Alessandro; Cortese, Andrea; Robinson-Papp, Jessica; Colton, Theodore; Rybin, Denis V; Bisbee, Alice B; Ando, Yukio; Ikeda, Shu-ichi; Seldin, David C; Merlini, Giampaolo; Skinner, Martha; Kelly, Jeffery W; Dyck, Peter J.
Affiliation
  • Berk JL; Amyloidosis Center, Departments of Medicine and Neurology, Boston University School of Medicine, Boston, Massachusetts.
  • Suhr OB; Department of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden.
  • Obici L; Amyloidosis Research and Treatment Center, Foundation IRCCS Policlinico San Matteo and Department of Molecular Medicine, University of Pavia, Pavia, Italy.
  • Sekijima Y; Department of Medicine, Shinshu University School of Medicine, Matsumoto, Japan.
  • Zeldenrust SR; Departments of Medicine and Neurology, Mayo Clinic, Rochester, Minnesota.
  • Yamashita T; Department of Neurology, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan.
  • Heneghan MA; Institute of Liver Studies, King's College Hospital Foundation Trust, London, England.
  • Gorevic PD; Departments of Medicine and Neurology, Mount Sinai School of Medicine, New York, New York.
  • Litchy WJ; Departments of Medicine and Neurology, Mayo Clinic, Rochester, Minnesota.
  • Wiesman JF; Amyloidosis Center, Departments of Medicine and Neurology, Boston University School of Medicine, Boston, Massachusetts.
  • Nordh E; Department of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden.
  • Corato M; Istituto Clinico Humanitas, Rozzano, Italy.
  • Lozza A; C. Mondino National Institute of Neurology, Foundation IRCCS, Pavia, Italy.
  • Cortese A; C. Mondino National Institute of Neurology, Foundation IRCCS, Pavia, Italy.
  • Robinson-Papp J; Departments of Medicine and Neurology, Mount Sinai School of Medicine, New York, New York.
  • Colton T; Department of Epidemiology, Boston University School of Public Health, Boston, Massachusetts.
  • Rybin DV; Data Coordinating Center, Boston University School of Public Health, Boston, Massachusetts.
  • Bisbee AB; Data Coordinating Center, Boston University School of Public Health, Boston, Massachusetts.
  • Ando Y; Department of Neurology, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan.
  • Ikeda S; Department of Medicine, Shinshu University School of Medicine, Matsumoto, Japan.
  • Seldin DC; Amyloidosis Center, Departments of Medicine and Neurology, Boston University School of Medicine, Boston, Massachusetts.
  • Merlini G; Amyloidosis Research and Treatment Center, Foundation IRCCS Policlinico San Matteo and Department of Molecular Medicine, University of Pavia, Pavia, Italy.
  • Skinner M; Amyloidosis Center, Departments of Medicine and Neurology, Boston University School of Medicine, Boston, Massachusetts.
  • Kelly JW; Departments of Chemistry and Molecular and Experimental Medicine and Skaggs Institute of Chemical Biology, Scripps Research Institute, La Jolla, California.
  • Dyck PJ; Departments of Medicine and Neurology, Mayo Clinic, Rochester, Minnesota.
JAMA ; 310(24): 2658-67, 2013 Dec 25.
Article in En | MEDLINE | ID: mdl-24368466
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Anti-Inflammatory Agents, Non-Steroidal / Diflunisal / Amyloid Neuropathies, Familial Type of study: Clinical_trials / Observational_studies / Prognostic_studies Limits: Aged / Female / Humans / Male / Middle aged Language: En Journal: JAMA Year: 2013 Type: Article
Fulltext
Print
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Anti-Inflammatory Agents, Non-Steroidal / Diflunisal / Amyloid Neuropathies, Familial Type of study: Clinical_trials / Observational_studies / Prognostic_studies Limits: Aged / Female / Humans / Male / Middle aged Language: En Journal: JAMA Year: 2013 Type: Article