A review of preclinical animal models utilised for TB vaccine evaluation in the context of recent human efficacy data.

McShane, Helen; Williams, Ann

McShane, Helen; Williams, Ann.

Affiliation

McShane H; The Jenner Institute, University of Oxford, Old Road Campus Research Building, Roosevelt Drive, Oxford OX3 7DQ, UK. Electronic address: Helen.mcshane@ndm.ox.ac.uk.
Williams A; Public Health England, Porton Down, Porton, Salisbury, UK. Electronic address: ann.rawkins@phe.gov.uk.

Tuberculosis (Edinb) ; 94(2): 105-10, 2014 Mar.

Article in En | MEDLINE | ID: mdl-24369986

Subject(s)

Mycobacterium tuberculosis/immunology; Tuberculosis Vaccines/pharmacology; Tuberculosis/prevention & control; Animals; BCG Vaccine/pharmacology; Cattle; Drug Design; Drug Evaluation, Preclinical; Guinea Pigs; Humans; Mice; Models, Animal; Practice Guidelines as Topic; Primates; Vaccines, DNA

Key words

Clinical; Efficacy; MVA85A; Pre-clinical; Vaccine

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Tuberculosis / Tuberculosis Vaccines / Mycobacterium tuberculosis Type of study: Guideline / Prognostic_studies Limits: Animals / Humans Language: En Journal: Tuberculosis (Edinb) Year: 2014 Type: Article

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