Alpha-tryptase gene variation is associated with levels of circulating IgE and lung function in asthma.

Abdelmotelb, A M; Rose-Zerilli, M J; Barton, S J; Holgate, S T; Walls, A F; Holloway, J W

Abdelmotelb, A M; Rose-Zerilli, M J; Barton, S J; Holgate, S T; Walls, A F; Holloway, J W.

Affiliation

Abdelmotelb AM; Clinical and Experimental Sciences Unit, Faculty of Medicine, University of Southampton, Southampton, UK; Faculty of Medicine, Tanta University, Tanta, Egypt.

Clin Exp Allergy ; 44(6): 822-30, 2014 Jun.

Article in En | MEDLINE | ID: mdl-24372627

Subject(s)

Asthma/etiology; Asthma/physiopathology; Genetic Variation; Immunoglobulin E/immunology; Tryptases/genetics; Adolescent; Adult; Alleles; Allergens/immunology; Animals; Asthma/diagnosis; Base Sequence; Child; DNA Copy Number Variations; Female; Gene Frequency; Genotype; Humans; Immunoglobulin E/blood; Male; Molecular Sequence Data; Phenotype; Pyroglyphidae/immunology; Respiratory Function Tests; Sequence Alignment; Tryptases/chemistry; Young Adult

Key words

IgE; asthma; gene copy number variation; mast cell; tryptase

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Asthma / Genetic Variation / Immunoglobulin E / Tryptases Type of study: Diagnostic_studies / Guideline / Prognostic_studies / Risk_factors_studies Limits: Adolescent / Adult / Animals / Child / Female / Humans / Male Language: En Journal: Clin Exp Allergy Journal subject: ALERGIA E IMUNOLOGIA Year: 2014 Type: Article Affiliation country: Egypt

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