Crystal structure of a bacterial unsaturated glucuronyl hydrolase with specificity for heparin.

Nakamichi, Yusuke; Mikami, Bunzo; Murata, Kousaku; Hashimoto, Wataru

Nakamichi, Yusuke; Mikami, Bunzo; Murata, Kousaku; Hashimoto, Wataru.

Affiliation

Nakamichi Y; From the Laboratory of Basic and Applied Molecular Biotechnology, Division of Food Science and Biotechnology, Graduate School of Agriculture, and.

J Biol Chem ; 289(8): 4787-97, 2014 Feb 21.

Article in En | MEDLINE | ID: mdl-24403065

Subject(s)

Disaccharides/metabolism; Glycoside Hydrolases/chemistry; Heparin/analogs & derivatives; Pedobacter/enzymology; Amino Acid Sequence; Crystallography, X-Ray; Disaccharides/chemistry; Electrophoresis, Polyacrylamide Gel; Glycosaminoglycans/chemistry; Glycosaminoglycans/metabolism; Glycoside Hydrolases/metabolism; Heparin/chemistry; Heparin/metabolism; Kinetics; Models, Molecular; Molecular Sequence Data; Mutant Proteins/chemistry; Mutant Proteins/metabolism; Sequence Alignment; Streptococcus/enzymology; Substrate Specificity

Key words

Chondroitin; Enzyme Structure; Glycosaminoglycan; Glycoside Hydrolases; Heparan Sulfate; Heparin; Streptococcus; X-ray Crystallography

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Heparin / Disaccharides / Pedobacter / Glycoside Hydrolases Type of study: Prognostic_studies Language: En Journal: J Biol Chem Year: 2014 Type: Article

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