Kindlin-3 enhances breast cancer progression and metastasis by activating Twist-mediated angiogenesis.

Sossey-Alaoui, Khalid; Pluskota, Elzbieta; Davuluri, Gangarao; Bialkowska, Katarzyna; Das, Mitali; Szpak, Dorota; Lindner, Daniel J; Downs-Kelly, Erinn; Thompson, Cheryl L; Plow, Edward F

Sossey-Alaoui, Khalid; Pluskota, Elzbieta; Davuluri, Gangarao; Bialkowska, Katarzyna; Das, Mitali; Szpak, Dorota; Lindner, Daniel J; Downs-Kelly, Erinn; Thompson, Cheryl L; Plow, Edward F.

Affiliation

Sossey-Alaoui K; 2Department of Molecular Cardiology, Cleveland Clinic Lerner Research Institute, 9500 Euclid Ave. NB50, Cleveland, OH 44195, USA. E.F.P., plowe@ccf.org.

FASEB J ; 28(5): 2260-71, 2014 May.

Article in En | MEDLINE | ID: mdl-24469992

Subject(s)

Breast Neoplasms/metabolism; Gene Expression Regulation, Neoplastic; Membrane Proteins/metabolism; Neoplasm Proteins/metabolism; Neovascularization, Pathologic; Nuclear Proteins/metabolism; Twist-Related Protein 1/metabolism; Animals; Cell Line, Tumor; Disease Progression; Female; Humans; Integrin beta1/metabolism; Mice; Mice, SCID; Neoplasm Metastasis; Protein Structure, Tertiary; Receptor, ErbB-2/metabolism; Receptors, Estrogen/metabolism; Receptors, Progesterone/metabolism; Vascular Endothelial Growth Factor A/metabolism

Key words

VEGF; VEGFR2; epithelial-to-mesenchymal-transition; integrins; tumor macrophages

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Breast Neoplasms / Nuclear Proteins / Gene Expression Regulation, Neoplastic / Twist-Related Protein 1 / Membrane Proteins / Neoplasm Proteins / Neovascularization, Pathologic Type of study: Prognostic_studies Limits: Animals / Female / Humans Language: En Journal: FASEB J Journal subject: BIOLOGIA / FISIOLOGIA Year: 2014 Type: Article

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