IgG from patients with Lambert-Eaton syndrome blocks voltage-dependent calcium channels.

Kim, Y I; Neher, E

Kim, Y I; Neher, E.

Affiliation

Kim YI; Department of Neurology, University of Virginia School of Medicine, Charlottesville 22908.

Science ; 239(4838): 405-8, 1988 Jan 22.

Article in En | MEDLINE | ID: mdl-2447652

Subject(s)

Autoimmune Diseases/immunology; Calcium/metabolism; Immunoglobulin G/physiology; Ion Channels/physiology; Neuromuscular Diseases/immunology; Adrenal Glands/physiopathology; Autoantibodies/physiology; Autoimmune Diseases/physiopathology; Benzofurans; Carcinoma, Small Cell/immunology; Cell Membrane/physiology; Chromaffin System/physiopathology; Electric Conductivity; Exocytosis; Fluorescent Dyes; Fura-2; Humans; Ion Channels/drug effects; Lung Neoplasms/immunology; Neuromuscular Diseases/physiopathology; Sodium/metabolism; Synapses/immunology; Synapses/physiology; Syndrome; Tetrodotoxin/pharmacology

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Collection: 01-internacional Database: MEDLINE Main subject: Autoimmune Diseases / Immunoglobulin G / Calcium / Ion Channels / Neuromuscular Diseases Limits: Humans Language: En Journal: Science Year: 1988 Type: Article

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