A molecular targeting against nuclear factor-&#954;B, as a chemotherapeutic approach for human malignant mesothelioma.

Nishikawa, Sho; Tanaka, Akane; Matsuda, Akira; Oida, Kumiko; Jang, Hyosun; Jung, Kyungsook; Amagai, Yosuke; Ahn, Ginae; Okamoto, Noriko; Ishizaka, Saori; Matsuda, Hiroshi

A molecular targeting against nuclear factor-κB, as a chemotherapeutic approach for human malignant mesothelioma.

Nishikawa, Sho; Tanaka, Akane; Matsuda, Akira; Oida, Kumiko; Jang, Hyosun; Jung, Kyungsook; Amagai, Yosuke; Ahn, Ginae; Okamoto, Noriko; Ishizaka, Saori; Matsuda, Hiroshi.

Affiliation

Nishikawa S; Cooperative Major in Advanced Health Science, Graduate School of Bio-Applications and System Engineering, Tokyo University of Agriculture and Technology, Fuchu, Tokyo, Japan.

Cancer Med ; 3(2): 416-25, 2014 Apr.

Article in En | MEDLINE | ID: mdl-24510578

Subject(s)

Lung Neoplasms/drug therapy; Mesothelioma/drug therapy; NF-kappa B/antagonists & inhibitors; NF-kappa B/metabolism; Animals; Antineoplastic Agents/pharmacology; Benzamides/pharmacology; Cell Cycle Checkpoints/drug effects; Cell Line, Tumor; Cell Proliferation/drug effects; Female; Glutamates/pharmacology; Guanine/analogs & derivatives; Guanine/pharmacology; Humans; Lung Neoplasms/metabolism; Lung Neoplasms/pathology; Mesothelioma/metabolism; Mesothelioma/pathology; Mesothelioma, Malignant; Mice; Mice, Inbred BALB C; Mice, SCID; Molecular Targeted Therapy; Pemetrexed; Xenograft Model Antitumor Assays

Key words

Animal model; NF-κB; cell cycle; mesothelioma

Fulltext

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: NF-kappa B / Lung Neoplasms / Mesothelioma Type of study: Prognostic_studies / Risk_factors_studies Limits: Animals / Female / Humans Language: En Journal: Cancer Med Year: 2014 Type: Article Affiliation country: Japan

Fulltext

XML

PubMed Links

Search on Google