LIMD1 antagonizes E2F1 activity and cell cycle progression by enhancing Rb function in cancer cells.

Mayank, Adarsh K; Sharma, Shipra; Deshwal, Ravi K; Lal, Sunil K

Mayank, Adarsh K; Sharma, Shipra; Deshwal, Ravi K; Lal, Sunil K.

Affiliation

Mayank AK; School of Life Sciences, Singhania University, Pacheri Beri, Rajasthan, India.

Cell Biol Int ; 38(7): 809-17, 2014 Jul.

Article in En | MEDLINE | ID: mdl-24523249

Subject(s)

E2F1 Transcription Factor/metabolism; Intracellular Signaling Peptides and Proteins/metabolism; LIM Domain Proteins/metabolism; Retinoblastoma Protein/metabolism; Cell Line, Tumor; Down-Regulation; E2F1 Transcription Factor/antagonists & inhibitors; G1 Phase Cell Cycle Checkpoints; Humans; Intracellular Signaling Peptides and Proteins/genetics; LIM Domain Proteins/genetics; Phosphorylation; Protein Binding

Key words

LIMD1; Rb phosphorylation; cell cycle; tumour suppressor

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Retinoblastoma Protein / Intracellular Signaling Peptides and Proteins / E2F1 Transcription Factor / LIM Domain Proteins Limits: Humans Language: En Journal: Cell Biol Int Year: 2014 Type: Article Affiliation country: India

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