Efficacy and safety of canagliflozin over 52 weeks in patients with type 2 diabetes on background metformin and pioglitazone.

Forst, T; Guthrie, R; Goldenberg, R; Yee, J; Vijapurkar, U; Meininger, G; Stein, P

Forst, T; Guthrie, R; Goldenberg, R; Yee, J; Vijapurkar, U; Meininger, G; Stein, P.

Affiliation

Forst T; Profil Mainz, Mainz, Germany; Johannes Gutenberg University, Mainz, Germany.

Diabetes Obes Metab ; 16(5): 467-77, 2014 May.

Article in En | MEDLINE | ID: mdl-24528605

Subject(s)

Blood Glucose/drug effects; Diabetes Mellitus, Type 2/drug therapy; Glucosides/therapeutic use; Hypoglycemic Agents/therapeutic use; Metformin/administration & dosage; Thiazolidinediones/administration & dosage; Thiophenes/therapeutic use; Blood Glucose/metabolism; Blood Pressure/drug effects; Canagliflozin; Candidiasis/chemically induced; Diabetes Mellitus, Type 2/blood; Diuretics, Osmotic/adverse effects; Double-Blind Method; Drug Therapy, Combination; Female; Genital Diseases, Female/chemically induced; Genital Diseases, Male/chemically induced; Glucosides/administration & dosage; Glucosides/adverse effects; Humans; Hypoglycemic Agents/administration & dosage; Hypoglycemic Agents/adverse effects; Lipids; Male; Middle Aged; Pioglitazone; Pyrazines/administration & dosage; Sitagliptin Phosphate; Thiophenes/administration & dosage; Thiophenes/adverse effects; Treatment Outcome; Triazoles/administration & dosage; Weight Loss

Key words

SGLT2 inhibitor; metformin; phase 3 study; thiazolidinediones; type 2 diabetes

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Thiophenes / Blood Glucose / Thiazolidinediones / Diabetes Mellitus, Type 2 / Glucosides / Hypoglycemic Agents / Metformin Type of study: Clinical_trials Limits: Female / Humans / Male / Middle aged Language: En Journal: Diabetes Obes Metab Journal subject: ENDOCRINOLOGIA / METABOLISMO Year: 2014 Type: Article Affiliation country: Germany

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