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Internalization of the chemokine receptor CCR4 can be evoked by orthosteric and allosteric receptor antagonists.
Ajram, Laura; Begg, Malcolm; Slack, Robert; Cryan, Jenni; Hall, David; Hodgson, Simon; Ford, Alison; Barnes, Ashley; Swieboda, Dawid; Mousnier, Aurelie; Solari, Roberto.
Affiliation
  • Ajram L; Respiratory Therapy Area, GlaxoSmithKline, Gunnels Wood Road, Stevenage, Herts SG1 2NY, UK.
  • Begg M; Respiratory Therapy Area, GlaxoSmithKline, Gunnels Wood Road, Stevenage, Herts SG1 2NY, UK.
  • Slack R; Respiratory Therapy Area, GlaxoSmithKline, Gunnels Wood Road, Stevenage, Herts SG1 2NY, UK.
  • Cryan J; Platform Technology Sciences, GlaxoSmithKline, Gunnels Wood Road, Stevenage, Herts SG1 2NY, UK.
  • Hall D; Respiratory Therapy Area, GlaxoSmithKline, Gunnels Wood Road, Stevenage, Herts SG1 2NY, UK.
  • Hodgson S; Respiratory Therapy Area, GlaxoSmithKline, Gunnels Wood Road, Stevenage, Herts SG1 2NY, UK.
  • Ford A; Respiratory Therapy Area, GlaxoSmithKline, Gunnels Wood Road, Stevenage, Herts SG1 2NY, UK.
  • Barnes A; Platform Technology Sciences, GlaxoSmithKline, Gunnels Wood Road, Stevenage, Herts SG1 2NY, UK.
  • Swieboda D; Airway Disease Infection Section, National Heart and Lung Institute, Imperial College, Norfolk Place, London W2 1PG, UK.
  • Mousnier A; Airway Disease Infection Section, National Heart and Lung Institute, Imperial College, Norfolk Place, London W2 1PG, UK.
  • Solari R; Respiratory Therapy Area, GlaxoSmithKline, Gunnels Wood Road, Stevenage, Herts SG1 2NY, UK; Airway Disease Infection Section, National Heart and Lung Institute, Imperial College, Norfolk Place, London W2 1PG, UK. Electronic address: r.solari@imperial.ac.uk.
Eur J Pharmacol ; 729: 75-85, 2014 Apr 15.
Article in En | MEDLINE | ID: mdl-24534492
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Chemotaxis / Endocytosis / Receptors, CCR4 Limits: Animals / Humans Language: En Journal: Eur J Pharmacol Year: 2014 Type: Article Affiliation country: United kingdom
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Chemotaxis / Endocytosis / Receptors, CCR4 Limits: Animals / Humans Language: En Journal: Eur J Pharmacol Year: 2014 Type: Article Affiliation country: United kingdom