GCNF-dependent activation of cyclin D1 expression via repression of Mir302a during ESC differentiation.

Wang, Hongran; Wang, Xiaohong; Archer, Trevor K; Zwaka, Thomas P; Cooney, Austin J

Wang, Hongran; Wang, Xiaohong; Archer, Trevor K; Zwaka, Thomas P; Cooney, Austin J.

Affiliation

Wang H; Department of Molecular and Cellular Biology, Baylor College of Medicine, One Baylor Plaza, Houston, Texas, USA; Department of Surgery, Baylor College of Medicine, One Baylor Plaza, Houston, Texas, USA.

Stem Cells ; 32(6): 1527-37, 2014 Jun.

Article in En | MEDLINE | ID: mdl-24578347

Subject(s)

Cell Differentiation/genetics; Cyclin D1/genetics; Embryonic Stem Cells/cytology; Embryonic Stem Cells/metabolism; Nuclear Receptor Subfamily 6, Group A, Member 1/metabolism; Repressor Proteins/metabolism; Animals; Cell Proliferation; Cell Shape; Colony-Forming Units Assay; Cyclin D1/metabolism; Embryo, Mammalian/cytology; Embryo, Mammalian/metabolism; Gene Expression Regulation, Developmental; Mice; MicroRNAs/genetics; MicroRNAs/metabolism; Models, Biological; Nuclear Receptor Subfamily 6, Group A, Member 1/deficiency; Promoter Regions, Genetic/genetics; Protein Binding/genetics

Key words

Cyclin D1; ESCs; GCNF; Mir302; microRNA

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Repressor Proteins / Cell Differentiation / Cyclin D1 / Embryonic Stem Cells / Nuclear Receptor Subfamily 6, Group A, Member 1 Type of study: Prognostic_studies Limits: Animals Language: En Journal: Stem Cells Year: 2014 Type: Article Affiliation country: United States

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