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Tumor infiltrating lymphocytes are prognostic in triple negative breast cancer and predictive for trastuzumab benefit in early breast cancer: results from the FinHER trial.
Loi, S; Michiels, S; Salgado, R; Sirtaine, N; Jose, V; Fumagalli, D; Kellokumpu-Lehtinen, P-L; Bono, P; Kataja, V; Desmedt, C; Piccart, M J; Loibl, S; Denkert, C; Smyth, M J; Joensuu, H; Sotiriou, C.
Affiliation
  • Loi S; Breast Cancer Translational Research Laboratory, Institut Jules Bordet, Université Libre de Bruxelles, Brussels, Belgium Division of Research and Cancer Medicine, Peter MacCallum Cancer Centre, East Melbourne,Australia sherene.loi@petermac.org.
  • Michiels S; Breast Cancer Translational Research Laboratory, Institut Jules Bordet, Université Libre de Bruxelles, Brussels, Belgium Service de Biostatistique et D'Epidemiology, Gustave Roussy, Universite Paris-Sud, Villejuif, France.
  • Salgado R; Department of Anatomical Pathology, Institut Jules Bordet, Brussels, Belgium.
  • Sirtaine N; Department of Anatomical Pathology, Institut Jules Bordet, Brussels, Belgium.
  • Jose V; Breast Cancer Translational Research Laboratory, Institut Jules Bordet, Université Libre de Bruxelles, Brussels, Belgium.
  • Fumagalli D; Breast Cancer Translational Research Laboratory, Institut Jules Bordet, Université Libre de Bruxelles, Brussels, Belgium.
  • Kellokumpu-Lehtinen PL; Department of Oncology, Tampere University Hospital, Tampere.
  • Bono P; Department of Oncology, Helsinki University Central Hospital, Helsinki.
  • Kataja V; Cancer Center, Kuopio University Hospital, Kuopio, Finland.
  • Desmedt C; Breast Cancer Translational Research Laboratory, Institut Jules Bordet, Université Libre de Bruxelles, Brussels, Belgium.
  • Piccart MJ; Department of Medicine, Institut Jules Bordet, Brussels, Belgium.
  • Loibl S; German Breast Group, Neu-Isenburg.
  • Denkert C; Charité University Hospital, Institute of Pathology, Berlin, Germany.
  • Smyth MJ; Immunology in Cancer and Infection Laboratory, Queensland Institute of Medical Research (QIMR) Berghofer Medical Research Institute; School of Medicine, University of Queensland, Herston, Australia.
  • Joensuu H; Department of Oncology, Helsinki University Central Hospital, Helsinki.
  • Sotiriou C; Breast Cancer Translational Research Laboratory, Institut Jules Bordet, Université Libre de Bruxelles, Brussels, Belgium.
Ann Oncol ; 25(8): 1544-50, 2014 Aug.
Article in En | MEDLINE | ID: mdl-24608200
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Antineoplastic Combined Chemotherapy Protocols / Biomarkers, Tumor / Lymphocytes, Tumor-Infiltrating / Biomarkers, Pharmacological / Antibodies, Monoclonal, Humanized / Triple Negative Breast Neoplasms Type of study: Clinical_trials / Diagnostic_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Adult / Aged / Female / Humans / Middle aged Country/Region as subject: Europa Language: En Journal: Ann Oncol Journal subject: NEOPLASIAS Year: 2014 Type: Article Affiliation country: Australia
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Antineoplastic Combined Chemotherapy Protocols / Biomarkers, Tumor / Lymphocytes, Tumor-Infiltrating / Biomarkers, Pharmacological / Antibodies, Monoclonal, Humanized / Triple Negative Breast Neoplasms Type of study: Clinical_trials / Diagnostic_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Adult / Aged / Female / Humans / Middle aged Country/Region as subject: Europa Language: En Journal: Ann Oncol Journal subject: NEOPLASIAS Year: 2014 Type: Article Affiliation country: Australia