Metformin enhances tamoxifen-mediated tumor growth inhibition in ER-positive breast carcinoma.

Ma, Ji; Guo, Yan; Chen, Suning; Zhong, Cuiping; Xue, Yan; Zhang, Yuan; Lai, Xiaofeng; Wei, Yifang; Yu, Shentong; Zhang, Jian; Liu, Wenchao

Ma, Ji; Guo, Yan; Chen, Suning; Zhong, Cuiping; Xue, Yan; Zhang, Yuan; Lai, Xiaofeng; Wei, Yifang; Yu, Shentong; Zhang, Jian; Liu, Wenchao.

Affiliation

Zhang J; The State Key Laboratory of Cancer Biology and Department of Oncology, Xijing Hospital, The Fourth Military Medical University, Xi'an 710032, China. biozhangj@hotmail.com.

BMC Cancer ; 14: 172, 2014 Mar 11.

Article in En | MEDLINE | ID: mdl-24612549

Subject(s)

Antineoplastic Agents/pharmacology; Breast Neoplasms/drug therapy; Metformin/pharmacology; Receptors, Estrogen/metabolism; Tamoxifen/pharmacology; Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis/drug effects; Breast Neoplasms/pathology; Cell Line, Tumor; Cell Proliferation/drug effects; Female; Humans; MCF-7 Cells; Mammary Neoplasms, Experimental; Mice; Mice, Nude; Signal Transduction/drug effects; Xenograft Model Antitumor Assays

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Tamoxifen / Breast Neoplasms / Receptors, Estrogen / Metformin / Antineoplastic Agents Limits: Animals / Female / Humans Language: En Journal: BMC Cancer Journal subject: NEOPLASIAS Year: 2014 Type: Article

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