Directing group-controlled regioselectivity in an enzymatic C-H bond oxygenation.

Negretti, Solymar; Narayan, Alison R H; Chiou, Karoline C; Kells, Petrea M; Stachowski, Jessica L; Hansen, Douglas A; Podust, Larissa M; Montgomery, John; Sherman, David H

Negretti, Solymar; Narayan, Alison R H; Chiou, Karoline C; Kells, Petrea M; Stachowski, Jessica L; Hansen, Douglas A; Podust, Larissa M; Montgomery, John; Sherman, David H.

Affiliation

Negretti S; Department of Medicinal Chemistry, §Life Sciences Institute, â¥Department of Chemistry, and â¥Department of Microbiology & Immunology, University of Michigan , Ann Arbor, Michigan 48109, United States.

J Am Chem Soc ; 136(13): 4901-4, 2014 Apr 02.

Article in En | MEDLINE | ID: mdl-24627965

Subject(s)

Cytochrome P-450 Enzyme System/metabolism; Amino Sugars/chemistry; Amino Sugars/metabolism; Biocatalysis; Cytochrome P-450 Enzyme System/chemistry; Hydroxylation; Macrolides/chemistry; Macrolides/metabolism; Models, Molecular; Stereoisomerism; Substrate Specificity

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cytochrome P-450 Enzyme System Language: En Journal: J Am Chem Soc Year: 2014 Type: Article Affiliation country: United States

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