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MMP7-mediated cleavage of nucleolin at Asp255 induces MMP9 expression to promote tumor malignancy.
Hsu, T-I; Lin, S-C; Lu, P-S; Chang, W-C; Hung, C-Y; Yeh, Y-M; Su, W-C; Liao, P-C; Hung, J-J.
Affiliation
  • Hsu TI; 1] Institute of Bioinformatics and Biosignal Transduction, College of Bioscience and Biotechnology, National Cheng-Kung University, Tainan, Taiwan [2] Center for Infection Disease and Signal Transduction, National Cheng-Kung University, Tainan, Taiwan.
  • Lin SC; Institute of Bioinformatics and Biosignal Transduction, College of Bioscience and Biotechnology, National Cheng-Kung University, Tainan, Taiwan.
  • Lu PS; Institute of Bioinformatics and Biosignal Transduction, College of Bioscience and Biotechnology, National Cheng-Kung University, Tainan, Taiwan.
  • Chang WC; 1] Institute of Bioinformatics and Biosignal Transduction, College of Bioscience and Biotechnology, National Cheng-Kung University, Tainan, Taiwan [2] Center for Infection Disease and Signal Transduction, National Cheng-Kung University, Tainan, Taiwan [3] Institute of Basic Medical Sciences, Nationa
  • Hung CY; Institute of Basic Medical Sciences, National Cheng-Kung University, Tainan, Taiwan.
  • Yeh YM; Department of Internal Medicine, College of Medicine and Hospital, National Cheng-Kung University, Tainan, Taiwan.
  • Su WC; Department of Internal Medicine, College of Medicine and Hospital, National Cheng-Kung University, Tainan, Taiwan.
  • Liao PC; Department of Environmental and Occupational Health, National Cheng-Kung University, Tainan, Taiwan.
  • Hung JJ; 1] Institute of Bioinformatics and Biosignal Transduction, College of Bioscience and Biotechnology, National Cheng-Kung University, Tainan, Taiwan [2] Center for Infection Disease and Signal Transduction, National Cheng-Kung University, Tainan, Taiwan [3] Institute of Basic Medical Sciences, Nationa
Oncogene ; 34(7): 826-37, 2015 Feb 12.
Article in En | MEDLINE | ID: mdl-24632608
Subject(s)
Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Lung Neoplasms/metabolism; Matrix Metalloproteinase 7/metabolism; Matrix Metalloproteinase 9/biosynthesis; Phosphoproteins/metabolism; Proteolysis; RNA-Binding Proteins/metabolism; Adaptor Proteins, Signal Transducing/genetics; Adaptor Proteins, Signal Transducing/metabolism; Aged; Anaplastic Lymphoma Kinase; Animals; Autoantigens/genetics; Autoantigens/metabolism; Cell Cycle Proteins/genetics; Cell Cycle Proteins/metabolism; Female; Humans; Hypoxia-Inducible Factor 1, alpha Subunit/genetics; Hypoxia-Inducible Factor 1, alpha Subunit/metabolism; Kruppel-Like Factor 6; Kruppel-Like Transcription Factors/genetics; Kruppel-Like Transcription Factors/metabolism; Lung Neoplasms/genetics; Lung Neoplasms/pathology; Male; Matrix Metalloproteinase 7/genetics; Matrix Metalloproteinase 9/genetics; Mice; Mice, Nude; Neoplasm Metastasis; Nuclear Proteins/genetics; Nuclear Proteins/metabolism; Phosphoproteins/genetics; Proteins/genetics; Proteins/metabolism; Proto-Oncogene Proteins/genetics; Proto-Oncogene Proteins/metabolism; Proto-Oncogene Proteins c-cbl/genetics; Proto-Oncogene Proteins c-cbl/metabolism; RNA Stability/genetics; RNA, Messenger/genetics; RNA, Messenger/metabolism; RNA, Neoplasm/genetics; RNA, Neoplasm/metabolism; RNA-Binding Proteins/genetics; Receptor Protein-Tyrosine Kinases/genetics; Receptor Protein-Tyrosine Kinases/metabolism; Transcription Factors/genetics; Transcription Factors/metabolism; Nucleolin
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Phosphoproteins / Gene Expression Regulation, Enzymologic / Gene Expression Regulation, Neoplastic / RNA-Binding Proteins / Matrix Metalloproteinase 9 / Matrix Metalloproteinase 7 / Proteolysis / Lung Neoplasms Type of study: Prognostic_studies Language: En Journal: Oncogene Journal subject: BIOLOGIA MOLECULAR / NEOPLASIAS Year: 2015 Type: Article Affiliation country: Taiwan
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Phosphoproteins / Gene Expression Regulation, Enzymologic / Gene Expression Regulation, Neoplastic / RNA-Binding Proteins / Matrix Metalloproteinase 9 / Matrix Metalloproteinase 7 / Proteolysis / Lung Neoplasms Type of study: Prognostic_studies Language: En Journal: Oncogene Journal subject: BIOLOGIA MOLECULAR / NEOPLASIAS Year: 2015 Type: Article Affiliation country: Taiwan