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Signaling by IL-6 promotes alternative activation of macrophages to limit endotoxemia and obesity-associated resistance to insulin.
Mauer, Jan; Chaurasia, Bhagirath; Goldau, Julia; Vogt, Merly C; Ruud, Johan; Nguyen, Khoa D; Theurich, Sebastian; Hausen, A Christine; Schmitz, Joel; Brönneke, Hella S; Estevez, Emma; Allen, Tamara L; Mesaros, Andrea; Partridge, Linda; Febbraio, Mark A; Chawla, Ajay; Wunderlich, F Thomas; Brüning, Jens C.
Affiliation
  • Mauer J; 1] Department of Mouse Genetics and Metabolism, Institute for Genetics, University of Cologne, Cologne, Germany. [2] Max Planck Institute for Neurological Research, Cologne, Germany. [3] Cologne Excellence Cluster on Cellular Stress Responses in Aging Associated Diseases, Cologne, Germany. [4].
  • Chaurasia B; 1] Department of Mouse Genetics and Metabolism, Institute for Genetics, University of Cologne, Cologne, Germany. [2].
  • Goldau J; Department of Mouse Genetics and Metabolism, Institute for Genetics, University of Cologne, Cologne, Germany.
  • Vogt MC; 1] Department of Mouse Genetics and Metabolism, Institute for Genetics, University of Cologne, Cologne, Germany. [2] Max Planck Institute for Neurological Research, Cologne, Germany. [3] Cologne Excellence Cluster on Cellular Stress Responses in Aging Associated Diseases, Cologne, Germany.
  • Ruud J; 1] Department of Mouse Genetics and Metabolism, Institute for Genetics, University of Cologne, Cologne, Germany. [2] Max Planck Institute for Neurological Research, Cologne, Germany. [3] Cologne Excellence Cluster on Cellular Stress Responses in Aging Associated Diseases, Cologne, Germany.
  • Nguyen KD; Cardiovascular Research Institute, Departments of Physiology and Medicine, University of California, San Francisco, California, USA.
  • Theurich S; 1] Department of Mouse Genetics and Metabolism, Institute for Genetics, University of Cologne, Cologne, Germany. [2] Max Planck Institute for Neurological Research, Cologne, Germany. [3] Cologne Excellence Cluster on Cellular Stress Responses in Aging Associated Diseases, Cologne, Germany.
  • Hausen AC; 1] Department of Mouse Genetics and Metabolism, Institute for Genetics, University of Cologne, Cologne, Germany. [2] Max Planck Institute for Neurological Research, Cologne, Germany. [3] Cologne Excellence Cluster on Cellular Stress Responses in Aging Associated Diseases, Cologne, Germany.
  • Schmitz J; 1] Department of Mouse Genetics and Metabolism, Institute for Genetics, University of Cologne, Cologne, Germany. [2] Center for Endocrinology, Diabetes and Preventive Medicine, University Hospital Cologne, Cologne, Germany. [3] Center for Molecular Medicine Cologne, Cologne, Germany.
  • Brönneke HS; 1] Max Planck Institute for Neurological Research, Cologne, Germany. [2] Cologne Excellence Cluster on Cellular Stress Responses in Aging Associated Diseases, Cologne, Germany.
  • Estevez E; Cellular and Molecular Metabolism Laboratory, Baker IDI Heart and Diabetes Institute, Melbourne, Australia.
  • Allen TL; Cellular and Molecular Metabolism Laboratory, Baker IDI Heart and Diabetes Institute, Melbourne, Australia.
  • Mesaros A; Max Planck Institute for Biology of Ageing, Cologne, Germany.
  • Partridge L; Max Planck Institute for Biology of Ageing, Cologne, Germany.
  • Febbraio MA; Cellular and Molecular Metabolism Laboratory, Baker IDI Heart and Diabetes Institute, Melbourne, Australia.
  • Chawla A; Cardiovascular Research Institute, Departments of Physiology and Medicine, University of California, San Francisco, California, USA.
  • Wunderlich FT; 1] Department of Mouse Genetics and Metabolism, Institute for Genetics, University of Cologne, Cologne, Germany. [2] Max Planck Institute for Neurological Research, Cologne, Germany. [3] Cologne Excellence Cluster on Cellular Stress Responses in Aging Associated Diseases, Cologne, Germany.
  • Brüning JC; 1] Department of Mouse Genetics and Metabolism, Institute for Genetics, University of Cologne, Cologne, Germany. [2] Max Planck Institute for Neurological Research, Cologne, Germany. [3] Cologne Excellence Cluster on Cellular Stress Responses in Aging Associated Diseases, Cologne, Germany. [4] Cente
Nat Immunol ; 15(5): 423-30, 2014 May.
Article in En | MEDLINE | ID: mdl-24681566

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Insulin Resistance / Interleukin-6 / Endotoxemia / Macrophage Activation / Macrophages / Obesity Type of study: Prognostic_studies / Risk_factors_studies Limits: Animals / Humans Language: En Journal: Nat Immunol Journal subject: ALERGIA E IMUNOLOGIA Year: 2014 Type: Article

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Insulin Resistance / Interleukin-6 / Endotoxemia / Macrophage Activation / Macrophages / Obesity Type of study: Prognostic_studies / Risk_factors_studies Limits: Animals / Humans Language: En Journal: Nat Immunol Journal subject: ALERGIA E IMUNOLOGIA Year: 2014 Type: Article