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Humanized staphylococcal enterotoxin B (SEB)-specific monoclonal antibodies protect from SEB intoxication and Staphylococcus aureus infections alone or as adjunctive therapy with vancomycin.
Varshney, Avanish K; Wang, Xiaobo; MacIntyre, Jennifer; Zollner, Richard S; Kelleher, Kerry; Kovalenko, Oleg V; Pechuan, Ximo; Byrne, Fergus R; Fries, Bettina C.
Affiliation
  • Varshney AK; Department of Medicine Department of Microbiology and Immunology.
  • Wang X; Department of Medicine Department of Microbiology and Immunology.
  • MacIntyre J; Pfizer Centers for Therapeutic Innovation, New York, New York.
  • Zollner RS; Pfizer Global BioTechnologies, Cambridge, Massachusetts.
  • Kelleher K; Pfizer Global BioTechnologies, Cambridge, Massachusetts.
  • Kovalenko OV; Pfizer Global BioTechnologies, Cambridge, Massachusetts.
  • Pechuan X; Department of Systems and Computational Biology, Albert Einstein College of Medicine, Bronx.
  • Byrne FR; Pfizer Centers for Therapeutic Innovation, New York, New York.
  • Fries BC; Department of Medicine Department of Microbiology and Immunology.
J Infect Dis ; 210(6): 973-81, 2014 Sep 15.
Article in En | MEDLINE | ID: mdl-24803533

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Staphylococcal Infections / Vancomycin / Enterotoxins / Methicillin-Resistant Staphylococcus aureus / Antibodies, Monoclonal, Humanized / Anti-Bacterial Agents Limits: Animals Language: En Journal: J Infect Dis Year: 2014 Type: Article

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Staphylococcal Infections / Vancomycin / Enterotoxins / Methicillin-Resistant Staphylococcus aureus / Antibodies, Monoclonal, Humanized / Anti-Bacterial Agents Limits: Animals Language: En Journal: J Infect Dis Year: 2014 Type: Article