Maintenance of dimer conformation by the dengue virus core protein &#945;4-&#945;4' helix pair is critical for nucleocapsid formation and virus production.

Teoh, Pak-Guan; Huang, Zhi-Shun; Pong, Wen-Li; Chen, Po-Chiang; Wu, Huey-Nan

Maintenance of dimer conformation by the dengue virus core protein α4-α4' helix pair is critical for nucleocapsid formation and virus production.

Teoh, Pak-Guan; Huang, Zhi-Shun; Pong, Wen-Li; Chen, Po-Chiang; Wu, Huey-Nan.

Affiliation

Teoh PG; Molecular Cell Biology, Taiwan International Graduate Program, Academia Sinica and Graduate Institute of Life Science, National Defense Medical Center, Taipei, Taiwan Institute of Molecular Biology, Academia Sinica, Taipei, Taiwan.
Huang ZS; Institute of Molecular Biology, Academia Sinica, Taipei, Taiwan.
Pong WL; Institute of Molecular Biology, Academia Sinica, Taipei, Taiwan.
Chen PC; Institute of Molecular Biology, Academia Sinica, Taipei, Taiwan.
Wu HN; Institute of Molecular Biology, Academia Sinica, Taipei, Taiwan hnwu@gate.sinica.edu.tw.

J Virol ; 88(14): 7998-8015, 2014 Jul.

Article in En | MEDLINE | ID: mdl-24807709

Subject(s)

Dengue Virus/physiology; Nucleocapsid/metabolism; Protein Multimerization; RNA, Viral/metabolism; Viral Core Proteins/metabolism; Virus Assembly; Aedes; Amino Acid Sequence; Animals; Cell Line; Cricetinae; Models, Molecular; Protein Conformation

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: RNA, Viral / Viral Core Proteins / Virus Assembly / Nucleocapsid / Dengue Virus / Protein Multimerization Limits: Animals Language: En Journal: J Virol Year: 2014 Type: Article Affiliation country: Taiwan

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