Etanercept blocks inflammatory responses orchestrated by TNF-&#945; to promote transplanted cell engraftment and proliferation in rat liver.

Viswanathan, Preeti; Kapoor, Sorabh; Kumaran, Vinay; Joseph, Brigid; Gupta, Sanjeev

Etanercept blocks inflammatory responses orchestrated by TNF-α to promote transplanted cell engraftment and proliferation in rat liver.

Viswanathan, Preeti; Kapoor, Sorabh; Kumaran, Vinay; Joseph, Brigid; Gupta, Sanjeev.

Affiliation

Viswanathan P; Division of Pediatric Gastroenterology, Department of Pediatrics, Children's Hospital at Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, NY.

Hepatology ; 60(4): 1378-88, 2014 Oct.

Article in En | MEDLINE | ID: mdl-24844924

Subject(s)

Cell Proliferation/physiology; Cell Transplantation; Hepatocytes/transplantation; Immunoglobulin G/therapeutic use; Inflammation/prevention & control; Receptors, Tumor Necrosis Factor/therapeutic use; Tumor Necrosis Factor-alpha/antagonists & inhibitors; Animals; Anti-Inflammatory Agents, Non-Steroidal/pharmacology; Anti-Inflammatory Agents, Non-Steroidal/therapeutic use; Cell Proliferation/drug effects; Cells, Cultured; Cytokines/metabolism; Etanercept; Immunoglobulin G/pharmacology; Inflammation/physiopathology; Kupffer Cells/drug effects; Liver/metabolism; Liver/pathology; Liver/surgery; Models, Animal; Neutrophils/drug effects; Rats; Rats, Inbred F344; Tumor Necrosis Factor-alpha/drug effects; Tumor Necrosis Factor-alpha/physiology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Immunoglobulin G / Tumor Necrosis Factor-alpha / Receptors, Tumor Necrosis Factor / Cell Transplantation / Hepatocytes / Cell Proliferation / Inflammation Type of study: Prognostic_studies Limits: Animals Language: En Journal: Hepatology Year: 2014 Type: Article

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