Impact of age on serum concentrations of venlafaxine and escitalopram in different CYP2D6 and CYP2C19 genotype subgroups.

Waade, Ragnhild Birkeland; Hermann, Monica; Moe, Hanne Lewis; Molden, Espen

Waade, Ragnhild Birkeland; Hermann, Monica; Moe, Hanne Lewis; Molden, Espen.

Affiliation

Waade RB; Center for Psychopharmacology, Diakonhjemmet Hospital, PO Box 85 Vinderen, 0319, Oslo, Norway, ragnhild@waade.com.

Eur J Clin Pharmacol ; 70(8): 933-40, 2014 Aug.

Article in En | MEDLINE | ID: mdl-24858822

Subject(s)

Aging/metabolism; Citalopram/blood; Cyclohexanols/blood; Cytochrome P-450 CYP2C19/genetics; Cytochrome P-450 CYP2D6/genetics; Adult; Aged; Aged, 80 and over; Antidepressive Agents, Second-Generation/blood; Antidepressive Agents, Second-Generation/pharmacokinetics; Citalopram/pharmacokinetics; Cyclohexanols/pharmacokinetics; Female; Genotype; Humans; Male; Middle Aged; Selective Serotonin Reuptake Inhibitors/blood; Selective Serotonin Reuptake Inhibitors/pharmacokinetics; Venlafaxine Hydrochloride; Young Adult

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Aging / Citalopram / Cytochrome P-450 CYP2D6 / Cyclohexanols / Cytochrome P-450 CYP2C19 Limits: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Language: En Journal: Eur J Clin Pharmacol Year: 2014 Type: Article

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