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Hippo-independent activation of YAP by the GNAQ uveal melanoma oncogene through a trio-regulated rho GTPase signaling circuitry.
Feng, Xiaodong; Degese, Maria Sol; Iglesias-Bartolome, Ramiro; Vaque, Jose P; Molinolo, Alfredo A; Rodrigues, Murilo; Zaidi, M Raza; Ksander, Bruce R; Merlino, Glenn; Sodhi, Akrit; Chen, Qianming; Gutkind, J Silvio.
Affiliation
  • Feng X; Oral and Pharyngeal Cancer Branch, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, MD 20892-4340, USA; State Key Laboratory of Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, Sichuan 610041, China.
  • Degese MS; Oral and Pharyngeal Cancer Branch, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, MD 20892-4340, USA.
  • Iglesias-Bartolome R; Oral and Pharyngeal Cancer Branch, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, MD 20892-4340, USA.
  • Vaque JP; Oral and Pharyngeal Cancer Branch, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, MD 20892-4340, USA.
  • Molinolo AA; Oral and Pharyngeal Cancer Branch, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, MD 20892-4340, USA.
  • Rodrigues M; Wilmer Eye Institute, Johns Hopkins School of Medicine, Baltimore, MD 21287, USA.
  • Zaidi MR; Fels Institute for Cancer Research and Molecular Biology, Temple University School of Medicine, Philadelphia, PA 19140, USA.
  • Ksander BR; Schepens Eye Research Institute, Harvard Medical School, Boston, MA 02114, USA.
  • Merlino G; Laboratory of Cancer Biology and Genetics, National Cancer Institute, Bethesda, MD 20892, USA.
  • Sodhi A; Wilmer Eye Institute, Johns Hopkins School of Medicine, Baltimore, MD 21287, USA.
  • Chen Q; State Key Laboratory of Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, Sichuan 610041, China. Electronic address: qmchen@scu.edu.cn.
  • Gutkind JS; Oral and Pharyngeal Cancer Branch, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, MD 20892-4340, USA. Electronic address: sg39v@nih.gov.
Cancer Cell ; 25(6): 831-45, 2014 Jun 16.
Article in En | MEDLINE | ID: mdl-24882515
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Transcription Factors / Uveal Neoplasms / Nuclear Proteins / Protein Serine-Threonine Kinases / GTP-Binding Protein alpha Subunits / GTP Phosphohydrolases / Melanoma Type of study: Prognostic_studies Limits: Animals / Female / Humans Language: En Journal: Cancer Cell Journal subject: NEOPLASIAS Year: 2014 Type: Article Affiliation country: China
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Transcription Factors / Uveal Neoplasms / Nuclear Proteins / Protein Serine-Threonine Kinases / GTP-Binding Protein alpha Subunits / GTP Phosphohydrolases / Melanoma Type of study: Prognostic_studies Limits: Animals / Female / Humans Language: En Journal: Cancer Cell Journal subject: NEOPLASIAS Year: 2014 Type: Article Affiliation country: China