Novel function of the Fanconi anemia group J or RECQ1 helicase to disrupt protein-DNA complexes in a replication protein A-stimulated manner.

Sommers, Joshua A; Banerjee, Taraswi; Hinds, Twila; Wan, Bingbing; Wold, Marc S; Lei, Ming; Brosh, Robert M

Sommers, Joshua A; Banerjee, Taraswi; Hinds, Twila; Wan, Bingbing; Wold, Marc S; Lei, Ming; Brosh, Robert M.

Affiliation

Sommers JA; From the Laboratory of Molecular Gerontology, Biomedical Research Center, NIA, National Institutes of Health, Baltimore, Maryland 21224.
Banerjee T; From the Laboratory of Molecular Gerontology, Biomedical Research Center, NIA, National Institutes of Health, Baltimore, Maryland 21224.
Hinds T; From the Laboratory of Molecular Gerontology, Biomedical Research Center, NIA, National Institutes of Health, Baltimore, Maryland 21224.
Wan B; the Department of Biological Chemistry, University of Michigan Medical School, Ann Arbor, Michigan 48109, and.
Wold MS; the Department of Biochemistry, Carver College of Medicine, University of Iowa, Iowa City, Iowa 52242.
Lei M; the Department of Biological Chemistry, University of Michigan Medical School, Ann Arbor, Michigan 48109, and.
Brosh RM; From the Laboratory of Molecular Gerontology, Biomedical Research Center, NIA, National Institutes of Health, Baltimore, Maryland 21224, broshr@mail.nih.gov.

J Biol Chem ; 289(29): 19928-41, 2014 Jul 18.

Article in En | MEDLINE | ID: mdl-24895130

Subject(s)

Basic-Leucine Zipper Transcription Factors/metabolism; DNA/metabolism; Fanconi Anemia Complementation Group Proteins/metabolism; RecQ Helicases/metabolism; Replication Protein A/metabolism; Amino Acid Substitution; Base Sequence; DNA/chemistry; DNA/genetics; Deoxyribonuclease BamHI/metabolism; Exodeoxyribonucleases/metabolism; Humans; Macromolecular Substances/chemistry; Macromolecular Substances/metabolism; Nucleic Acid Conformation; Protein Binding; Recombinant Proteins/genetics; Recombinant Proteins/metabolism; Replication Protein A/genetics; Substrate Specificity; Telomeric Repeat Binding Protein 1/metabolism; Werner Syndrome Helicase

Key words

DNA Helicase; DNA Repair; DNA-binding Protein; FANCJ; Fanconi Anemia; Genetic Disease; Genomic Instability; RECQ1; Replication Protein A; Telomere

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: DNA / Basic-Leucine Zipper Transcription Factors / Replication Protein A / Fanconi Anemia Complementation Group Proteins / RecQ Helicases Limits: Humans Language: En Journal: J Biol Chem Year: 2014 Type: Article

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