Low infectivity of a novel avian-origin H7N9 influenza virus in pigs.
Arch Virol
; 159(10): 2745-9, 2014 Oct.
Article
in En
| MEDLINE
| ID: mdl-24906526
ABSTRACT
We studied the pathogenesis and transmissibility of a novel avian-origin H7N9 influenza virus in pigs. When pigs were infected with H7N9 influenza virus, they did not show any clear clinical signs (such as sneezing, fever and loss of body weight), and they shed viruses through their noses for 2 days after infection. No transmission occurred between infected and naïve pigs. Pigs suffered from mild pneumonia, which was accompanied by the induction of inflammatory cytokines and chemokines such as IL-8 and CCL1. Taken together, our results suggest that pigs may not play an active role in transmitting H7N9 influenza virus to mammals.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Orthomyxoviridae Infections
/
Influenza A Virus, H7N9 Subtype
Type of study:
Prognostic_studies
Limits:
Animals
Language:
En
Journal:
Arch Virol
Year:
2014
Type:
Article