Novel investigations on the protective role of the FVIII/VWF complex in inhibitor development.

Mannucci, P M; Shi, Q; Bonanad, S; Klamroth, R

Mannucci, P M; Shi, Q; Bonanad, S; Klamroth, R.

Affiliation

Mannucci PM; Scientific Direction, IRCCS Ca' Granda Foundation Maggiore Hospital, Milan, Italy.

Haemophilia ; 20 Suppl 6: 2-16, 2014 Sep.

Article in En | MEDLINE | ID: mdl-24975700

Subject(s)

Coagulants/therapeutic use; Factor VIII/therapeutic use; Hemophilia A/drug therapy; Immune Tolerance/drug effects; von Willebrand Factor/therapeutic use; Blood Coagulation Factor Inhibitors/blood; Coagulants/immunology; Drug Substitution; Factor VIII/antagonists & inhibitors; Factor VIII/immunology; Hemophilia A/immunology; Humans; Recombinant Proteins/immunology; Recombinant Proteins/therapeutic use; von Willebrand Factor/antagonists & inhibitors; von Willebrand Factor/immunology

Key words

factor VIII; inhibitors; posttranslational modifications; preformed complex; surface plasmon resonance; von Willebrand factor

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Factor VIII / Von Willebrand Factor / Coagulants / Hemophilia A / Immune Tolerance Type of study: Clinical_trials Limits: Humans Language: En Journal: Haemophilia Journal subject: HEMATOLOGIA Year: 2014 Type: Article Affiliation country: Italy

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