Cellular signaling circuits interfaced with synthetic, post-translational, negating Boolean logic devices.

Razavi, Shiva; Su, Steven; Inoue, Takanari

Razavi, Shiva; Su, Steven; Inoue, Takanari.

Affiliation

Razavi S; Department of Biomedical Engineering, §Department of Cell Biology, and â¥Center for Cell Dynamics, Johns Hopkins University School of Medicine , Baltimore, Maryland 21205, United States.

ACS Synth Biol ; 3(9): 676-85, 2014 Sep 19.

Article in En | MEDLINE | ID: mdl-25000210

Subject(s)

Algorithms; Models, Theoretical; Animals; Anti-Bacterial Agents/pharmacology; COS Cells; Chlorocebus aethiops; Luminescent Proteins/genetics; Luminescent Proteins/metabolism; Microscopy, Confocal; Mitochondria/drug effects; Mitochondria/metabolism; Protein Multimerization; Protein Processing, Post-Translational; Signal Transduction/drug effects; Sirolimus/pharmacology; Tacrolimus Binding Proteins/genetics; Tacrolimus Binding Proteins/metabolism; Transfection; Red Fluorescent Protein

Key words

Rac; chemically induced dimerization; membrane ruffling; negation; signaling pathway; synthetic Boolean logic

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Algorithms / Models, Theoretical Limits: Animals Language: En Journal: ACS Synth Biol Year: 2014 Type: Article Affiliation country: United States

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