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High-fat-diet-mediated dysbiosis promotes intestinal carcinogenesis independently of obesity.
Schulz, Manon D; Atay, Cigdem; Heringer, Jessica; Romrig, Franziska K; Schwitalla, Sarah; Aydin, Begüm; Ziegler, Paul K; Varga, Julia; Reindl, Wolfgang; Pommerenke, Claudia; Salinas-Riester, Gabriela; Böck, Andreas; Alpert, Carl; Blaut, Michael; Polson, Sara C; Brandl, Lydia; Kirchner, Thomas; Greten, Florian R; Polson, Shawn W; Arkan, Melek C.
Affiliation
  • Schulz MD; 1] Institute of Molecular Immunology, Klinikum rechts der Isar, Technical University Munich, 81675 Munich, Germany [2].
  • Atay C; 1] Institute of Molecular Immunology, Klinikum rechts der Isar, Technical University Munich, 81675 Munich, Germany [2].
  • Heringer J; 1] Institute of Molecular Immunology, Klinikum rechts der Isar, Technical University Munich, 81675 Munich, Germany [2].
  • Romrig FK; Institute of Molecular Immunology, Klinikum rechts der Isar, Technical University Munich, 81675 Munich, Germany.
  • Schwitalla S; Institute of Molecular Immunology, Klinikum rechts der Isar, Technical University Munich, 81675 Munich, Germany.
  • Aydin B; Department of Molecular Biology and Genetics, Bogazici University, 34342 Bebek, Istanbul, Turkey.
  • Ziegler PK; 1] Georg-Speyer-Haus, Institute for Tumor Biology and Experimental Therapy, 60596 Frankfurt am Main, Germany [2] German Cancer Consortium (DKTK), 69120 Heidelberg, Germany [3] German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany.
  • Varga J; 1] Georg-Speyer-Haus, Institute for Tumor Biology and Experimental Therapy, 60596 Frankfurt am Main, Germany [2] German Cancer Consortium (DKTK), 69120 Heidelberg, Germany [3] German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany.
  • Reindl W; Department of Internal Medicine II, Universitätsmedizin Mannheim, Medical Faculty Mannheim, Heidelberg University, 68167 Mannheim, Germany.
  • Pommerenke C; Microarray and Deep-Sequencing Core Facility, University Medical Center Göttingen, 37077 Göttingen, Germany.
  • Salinas-Riester G; Microarray and Deep-Sequencing Core Facility, University Medical Center Göttingen, 37077 Göttingen, Germany.
  • Böck A; Institute for Mathematical Statistics, Technical University Munich, 81675 Munich, Germany.
  • Alpert C; 1] Department of Gastrointestinal Microbiology, German Institute of Human Nutrition Potsdam-Rehbruecke, 14558 Nuthetal, Germany [2].
  • Blaut M; Department of Gastrointestinal Microbiology, German Institute of Human Nutrition Potsdam-Rehbruecke, 14558 Nuthetal, Germany.
  • Polson SC; Center for Bioinformatics and Computational Biology, Delaware Biotechnology Institute, University of Delaware, Newark, Delaware 19711, USA.
  • Brandl L; Institute of Pathology, Ludwig Maximilians University, 80337 Munich, Germany.
  • Kirchner T; 1] German Cancer Consortium (DKTK), 69120 Heidelberg, Germany [2] German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany [3] Institute of Pathology, Ludwig Maximilians University, 80337 Munich, Germany.
  • Greten FR; 1] Georg-Speyer-Haus, Institute for Tumor Biology and Experimental Therapy, 60596 Frankfurt am Main, Germany [2] German Cancer Consortium (DKTK), 69120 Heidelberg, Germany [3] German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany.
  • Polson SW; Center for Bioinformatics and Computational Biology, Delaware Biotechnology Institute, University of Delaware, Newark, Delaware 19711, USA.
  • Arkan MC; Institute of Molecular Immunology, Klinikum rechts der Isar, Technical University Munich, 81675 Munich, Germany.
Nature ; 514(7523): 508-12, 2014 Oct 23.
Article in En | MEDLINE | ID: mdl-25174708
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Dietary Fats / Diet, High-Fat / Carcinogenesis / Dysbiosis / Intestinal Neoplasms / Obesity Type of study: Risk_factors_studies Limits: Animals Language: En Journal: Nature Year: 2014 Type: Article
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Dietary Fats / Diet, High-Fat / Carcinogenesis / Dysbiosis / Intestinal Neoplasms / Obesity Type of study: Risk_factors_studies Limits: Animals Language: En Journal: Nature Year: 2014 Type: Article