Bioavailability, distribution and clearance of tracheally-instilled and gavaged uncoated or silica-coated zinc oxide nanoparticles.

Konduru, Nagarjun V; Murdaugh, Kimberly M; Sotiriou, Georgios A; Donaghey, Thomas C; Demokritou, Philip; Brain, Joseph D; Molina, Ramon M

Konduru, Nagarjun V; Murdaugh, Kimberly M; Sotiriou, Georgios A; Donaghey, Thomas C; Demokritou, Philip; Brain, Joseph D; Molina, Ramon M.

Affiliation

Molina RM; Center for Nanotechnology and Nanotoxicology, Molecular and Integrative Physiological Sciences Program, Department of Environmental Health, School of Public Health, Harvard University, 665 Huntington Avenue, Boston 02115, MA, USA. rmolina@hsph.harvard.edu.

Part Fibre Toxicol ; 11: 44, 2014 Sep 03.

Article in En | MEDLINE | ID: mdl-25183210

Subject(s)

Inhalation Exposure; Nanoparticles/administration & dosage; Silicon Dioxide/administration & dosage; Silicon Dioxide/pharmacokinetics; Zinc Oxide/administration & dosage; Zinc Oxide/pharmacokinetics; Administration, Oral; Animals; Biological Availability; Half-Life; Inhalation Exposure/adverse effects; Lung/metabolism; Lymph Nodes/metabolism; Male; Metabolic Clearance Rate; Muscle, Skeletal/metabolism; Nanoparticles/chemistry; Nanoparticles/toxicity; Pneumonia/chemically induced; Rats; Rats, Wistar; Silicon Dioxide/chemical synthesis; Silicon Dioxide/toxicity; Tissue Distribution; Zinc Oxide/analogs & derivatives; Zinc Oxide/chemical synthesis; Zinc Oxide/toxicity

Fulltext

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Zinc Oxide / Silicon Dioxide / Inhalation Exposure / Nanoparticles Limits: Animals Language: En Journal: Part Fibre Toxicol Journal subject: TOXICOLOGIA Year: 2014 Type: Article

Fulltext

XML

PubMed Links

Search on Google