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Piperazinyl-oxadiazoles as selective sphingosine-1-phosphate receptor agonists.
Horan, Joshua C; Sanyal, Sulagna; Choi, Younggi; Hill-Drzewi, Melissa; Patnaude, Lori; Anderson, Shawn; Fogal, Steve; Mao, Can; Cook, Brian N; Gueneva-Boucheva, Kristina; Fisher, Michael B; Hickey, Eugene; Pack, Edward; Bannen, Lynne C; Chan, Diva S; Mac, Morrison B; Ng, Stephanie M; Wang, Yong; Xu, Wei; Modis, Louise K; Lemieux, René M.
Affiliation
  • Horan JC; Medicinal Chemistry, Boehringer Ingelheim Pharmaceuticals, 900 Ridgebury Rd, Ridgefield, CT 06877, United States. Electronic address: josh.horan@boehringer-ingelheim.com.
  • Sanyal S; Medicinal Chemistry, Boehringer Ingelheim Pharmaceuticals, 900 Ridgebury Rd, Ridgefield, CT 06877, United States.
  • Choi Y; Medicinal Chemistry, Boehringer Ingelheim Pharmaceuticals, 900 Ridgebury Rd, Ridgefield, CT 06877, United States.
  • Hill-Drzewi M; Medicinal Chemistry, Boehringer Ingelheim Pharmaceuticals, 900 Ridgebury Rd, Ridgefield, CT 06877, United States.
  • Patnaude L; Inflammation and Immunology, Boehringer Ingelheim Pharmaceuticals, 900 Ridgebury Rd, Ridgefield, CT 06877, United States.
  • Anderson S; Inflammation and Immunology, Boehringer Ingelheim Pharmaceuticals, 900 Ridgebury Rd, Ridgefield, CT 06877, United States.
  • Fogal S; Inflammation and Immunology, Boehringer Ingelheim Pharmaceuticals, 900 Ridgebury Rd, Ridgefield, CT 06877, United States.
  • Mao C; Medicinal Chemistry, Boehringer Ingelheim Pharmaceuticals, 900 Ridgebury Rd, Ridgefield, CT 06877, United States.
  • Cook BN; Medicinal Chemistry, Boehringer Ingelheim Pharmaceuticals, 900 Ridgebury Rd, Ridgefield, CT 06877, United States.
  • Gueneva-Boucheva K; Medicinal Chemistry, Boehringer Ingelheim Pharmaceuticals, 900 Ridgebury Rd, Ridgefield, CT 06877, United States.
  • Fisher MB; Medicinal Chemistry, Boehringer Ingelheim Pharmaceuticals, 900 Ridgebury Rd, Ridgefield, CT 06877, United States.
  • Hickey E; Medicinal Chemistry, Boehringer Ingelheim Pharmaceuticals, 900 Ridgebury Rd, Ridgefield, CT 06877, United States.
  • Pack E; Medicinal Chemistry, Boehringer Ingelheim Pharmaceuticals, 900 Ridgebury Rd, Ridgefield, CT 06877, United States.
  • Bannen LC; Medicinal Chemistry, Exelixis, 210 East Grand Avenue, South San Francisco, CA 94080, United States.
  • Chan DS; Medicinal Chemistry, Exelixis, 210 East Grand Avenue, South San Francisco, CA 94080, United States.
  • Mac MB; Medicinal Chemistry, Exelixis, 210 East Grand Avenue, South San Francisco, CA 94080, United States.
  • Ng SM; Medicinal Chemistry, Exelixis, 210 East Grand Avenue, South San Francisco, CA 94080, United States.
  • Wang Y; Medicinal Chemistry, Exelixis, 210 East Grand Avenue, South San Francisco, CA 94080, United States.
  • Xu W; Medicinal Chemistry, Exelixis, 210 East Grand Avenue, South San Francisco, CA 94080, United States.
  • Modis LK; Inflammation and Immunology, Boehringer Ingelheim Pharmaceuticals, 900 Ridgebury Rd, Ridgefield, CT 06877, United States.
  • Lemieux RM; Medicinal Chemistry, Boehringer Ingelheim Pharmaceuticals, 900 Ridgebury Rd, Ridgefield, CT 06877, United States.
Bioorg Med Chem Lett ; 24(20): 4807-11, 2014 Oct 15.
Article in En | MEDLINE | ID: mdl-25241927
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Oxadiazoles / Piperazines / Receptors, Lysosphingolipid Limits: Animals Language: En Journal: Bioorg Med Chem Lett Journal subject: BIOQUIMICA / QUIMICA Year: 2014 Type: Article
Fulltext
Print
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Oxadiazoles / Piperazines / Receptors, Lysosphingolipid Limits: Animals Language: En Journal: Bioorg Med Chem Lett Journal subject: BIOQUIMICA / QUIMICA Year: 2014 Type: Article