Peptide-bridged dinuclear Ru(II) complex for mitochondrial targeted monitoring of dynamic changes to oxygen concentration and ROS generation in live mammalian cells.

Martin, Aaron; Byrne, Aisling; Burke, Christopher S; Forster, Robert J; Keyes, Tia E

Martin, Aaron; Byrne, Aisling; Burke, Christopher S; Forster, Robert J; Keyes, Tia E.

Affiliation

Martin A; School of Chemical Sciences, National Biophotonics and Imaging Platform, Dublin City University , Dublin 9, Ireland.

J Am Chem Soc ; 136(43): 15300-9, 2014 Oct 29.

Article in En | MEDLINE | ID: mdl-25265566

Subject(s)

Mitochondria/metabolism; Molecular Probes/chemistry; Oligopeptides/chemistry; Organometallic Compounds/chemistry; Oxygen/metabolism; Reactive Oxygen Species/metabolism; Ruthenium/chemistry; Amino Acid Sequence; Antimycin A/pharmacology; Biological Transport; Cell Membrane Permeability; Cell Survival/drug effects; HeLa Cells; Humans; Mitochondria/drug effects; Molecular Probes/metabolism; Molecular Probes/toxicity; Molecular Sequence Data; Optical Imaging; Organometallic Compounds/metabolism; Organometallic Compounds/toxicity; Temperature

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Oligopeptides / Organometallic Compounds / Oxygen / Ruthenium / Molecular Probes / Reactive Oxygen Species / Mitochondria Limits: Humans Language: En Journal: J Am Chem Soc Year: 2014 Type: Article Affiliation country: Ireland

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