A lentiviral sponge for miRNA-21 diminishes aerobic glycolysis in bladder cancer T24 cells via the PTEN/PI3K/AKT/mTOR axis.

Yang, Xiao; Cheng, Yidong; Li, Pengchao; Tao, Jun; Deng, Xiaheng; Zhang, Xiaolei; Gu, Min; Lu, Qiang; Yin, Changjun

Yang, Xiao; Cheng, Yidong; Li, Pengchao; Tao, Jun; Deng, Xiaheng; Zhang, Xiaolei; Gu, Min; Lu, Qiang; Yin, Changjun.

Affiliation

Yang X; Department of Urology, The First Affiliated Hospital, Nanjing Medical University, Nanjing, China.

Tumour Biol ; 36(1): 383-91, 2015 Jan.

Article in En | MEDLINE | ID: mdl-25266796

Subject(s)

Glycolysis; MicroRNAs/genetics; Signal Transduction; Cell Line, Tumor; Gene Expression; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Glucose/metabolism; Humans; Lentivirus; MicroRNAs/metabolism; PTEN Phosphohydrolase/metabolism; Phosphatidylinositol 3-Kinases/metabolism; Proto-Oncogene Proteins c-akt/metabolism; TOR Serine-Threonine Kinases/metabolism; Transduction, Genetic; Urinary Bladder Neoplasms

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Signal Transduction / MicroRNAs / Glycolysis Limits: Humans Language: En Journal: Tumour Biol Journal subject: NEOPLASIAS Year: 2015 Type: Article Affiliation country: China

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