Structure-activity relationships of thiostrepton derivatives: implications for rational drug design.

Wolf, Antje; Schoof, Sebastian; Baumann, Sascha; Arndt, Hans-Dieter; Kirschner, Karl N

Wolf, Antje; Schoof, Sebastian; Baumann, Sascha; Arndt, Hans-Dieter; Kirschner, Karl N.

Affiliation

Wolf A; Department Bioinformatics, Fraunhofer-Institute for Algorithms and Scientific Computing (SCAI), Schloss Birlinghoven, 53754, Sankt Augustin, Germany.

J Comput Aided Mol Des ; 28(12): 1205-15, 2014 Dec.

Article in En | MEDLINE | ID: mdl-25281020

Subject(s)

Drug Design; RNA, Ribosomal/chemistry; Structure-Activity Relationship; Thiostrepton/chemistry; Binding Sites; Crystallography, X-Ray; Models, Molecular; Protein Binding; RNA, Ribosomal/metabolism; Ribosomes/chemistry; Ribosomes/metabolism; Thiostrepton/therapeutic use

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Structure-Activity Relationship / Thiostrepton / RNA, Ribosomal / Drug Design Language: En Journal: J Comput Aided Mol Des Journal subject: BIOLOGIA MOLECULAR / ENGENHARIA BIOMEDICA Year: 2014 Type: Article Affiliation country: Germany

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