HERC2/USP20 coordinates CHK1 activation by modulating CLASPIN stability.

Zhu, Min; Zhao, Hongchang; Liao, Ji; Xu, Xingzhi

Zhu, Min; Zhao, Hongchang; Liao, Ji; Xu, Xingzhi.

Affiliation

Zhu M; Beijing Key Laboratory of DNA Damage Response and College of Life Sciences, Capital Normal University, Beijing 100048, China.
Zhao H; Beijing Key Laboratory of DNA Damage Response and College of Life Sciences, Capital Normal University, Beijing 100048, China.
Liao J; Beijing Key Laboratory of DNA Damage Response and College of Life Sciences, Capital Normal University, Beijing 100048, China.
Xu X; Beijing Key Laboratory of DNA Damage Response and College of Life Sciences, Capital Normal University, Beijing 100048, China Xingzhi_Xu@mail.cnu.edu.cn.

Nucleic Acids Res ; 42(21): 13074-81, 2014 Dec 01.

Article in En | MEDLINE | ID: mdl-25326330

Subject(s)

Adaptor Proteins, Signal Transducing/metabolism; Guanine Nucleotide Exchange Factors/metabolism; Protein Kinases/metabolism; Ubiquitin Thiolesterase/metabolism; Animals; Ataxia Telangiectasia Mutated Proteins/metabolism; Cell Line, Tumor; Checkpoint Kinase 1; DNA Replication; Enzyme Activation; Female; HEK293 Cells; Humans; Mice, Inbred BALB C; Mice, Nude; Neoplasms/pathology; Phosphorylation; Protein Stability; Stress, Physiological; Ubiquitin-Protein Ligases; Ultraviolet Rays

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Protein Kinases / Guanine Nucleotide Exchange Factors / Ubiquitin Thiolesterase / Adaptor Proteins, Signal Transducing Limits: Animals / Female / Humans Language: En Journal: Nucleic Acids Res Year: 2014 Type: Article Affiliation country: China

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