Life-span carcinogenicity studies on Sprague-Dawley rats exposed to Î³-radiation: design of the project and report on the tumor occurrence after post-natal radiation exposure (6 weeks of age) delivered in a single acute exposure.

Soffritti, Morando; Tibaldi, Eva; Bua, Luciano; Padovani, Michela; Falcioni, Laura; Lauriola, Michelina; Manservigi, Marco; Manservisi, Fabiana; Belpoggi, Fiorella

Soffritti, Morando; Tibaldi, Eva; Bua, Luciano; Padovani, Michela; Falcioni, Laura; Lauriola, Michelina; Manservigi, Marco; Manservisi, Fabiana; Belpoggi, Fiorella.

Affiliation

Soffritti M; Cesare Maltoni Cancer Research Center, Ramazzini Institute, Bologna, Italy.

Am J Ind Med ; 58(1): 46-60, 2015 Jan.

Article in En | MEDLINE | ID: mdl-25351660

Subject(s)

Gamma Rays/adverse effects; Neoplasms/epidemiology; Neoplasms/etiology; Animals; Autopsy; Carcinogenicity Tests; Disease Models, Animal; Dose-Response Relationship, Radiation; Female; Male; Neoplasms/classification; Proportional Hazards Models; Radiation Dosage; Rats; Rats, Sprague-Dawley; Research Design

Key words

carcinogenicity; life-span bioassay; low-dose; rat; Î³-radiation

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Gamma Rays / Neoplasms Type of study: Prognostic_studies Limits: Animals Language: En Journal: Am J Ind Med Year: 2015 Type: Article Affiliation country: Italy

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