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Cerebral small vessel disease-related protease HtrA1 processes latent TGF-ß binding protein 1 and facilitates TGF-ß signaling.
Beaufort, Nathalie; Scharrer, Eva; Kremmer, Elisabeth; Lux, Vanda; Ehrmann, Michael; Huber, Robert; Houlden, Henry; Werring, David; Haffner, Christof; Dichgans, Martin.
Affiliation
  • Beaufort N; Institute for Stroke and Dementia Research, Klinikum der Universität München, Ludwig Maximilians University, 81377 Munich, Germany;
  • Scharrer E; Institute for Stroke and Dementia Research, Klinikum der Universität München, Ludwig Maximilians University, 81377 Munich, Germany;
  • Kremmer E; Institute of Molecular Immunology, Helmholtz-Zentrum München, 81377 Munich, Germany;
  • Lux V; Centre for Medical Biotechnology, Faculty of Biology, University of Duisburg-Essen, 45141 Essen, Germany;
  • Ehrmann M; Centre for Medical Biotechnology, Faculty of Biology, University of Duisburg-Essen, 45141 Essen, Germany;
  • Huber R; Centre for Medical Biotechnology, Faculty of Biology, University of Duisburg-Essen, 45141 Essen, Germany; Emeritus Group Structure Research, Max Planck Institute of Biochemistry, 82152 Martinsried, Germany; Center for Integrated Protein Science at the Department of Chemistry, Lehrstuhl für Biochemie
  • Houlden H; Department of Molecular Neuroscience and Neurogenetics Laboratory, University College London (UCL) Institute of Neurology and The National Hospital for Neurology and Neurosurgery, London WC1N 3BG, United Kingdom;
  • Werring D; Stroke Research Group, Department of Brain Repair and Rehabilitation, UCL Institute of Neurology and The National Hospital for Neurology and Neurosurgery, London WC1N 3BG, United Kingdom; and.
  • Haffner C; Institute for Stroke and Dementia Research, Klinikum der Universität München, Ludwig Maximilians University, 81377 Munich, Germany; christof.haffner@med.uni-muenchen.de huber@biochem.mpg.de martin.dichgans@med.uni-muenchen.de.
  • Dichgans M; Institute for Stroke and Dementia Research, Klinikum der Universität München, Ludwig Maximilians University, 81377 Munich, Germany; Munich Cluster for Systems Neurology (SyNergy), 80336 Munich, Germany christof.haffner@med.uni-muenchen.de huber@biochem.mpg.de martin.dichgans@med.uni-muenchen.de.
Proc Natl Acad Sci U S A ; 111(46): 16496-501, 2014 Nov 18.
Article in En | MEDLINE | ID: mdl-25369932
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Spinal Diseases / Serine Endopeptidases / Cerebral Infarction / Alopecia / Transforming Growth Factor beta1 / Latent TGF-beta Binding Proteins / Leukoencephalopathies Type of study: Prognostic_studies Language: En Journal: Proc Natl Acad Sci U S A Year: 2014 Type: Article
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Spinal Diseases / Serine Endopeptidases / Cerebral Infarction / Alopecia / Transforming Growth Factor beta1 / Latent TGF-beta Binding Proteins / Leukoencephalopathies Type of study: Prognostic_studies Language: En Journal: Proc Natl Acad Sci U S A Year: 2014 Type: Article