Replication of human immunodeficiency virus in monocytes. Granulocyte/macrophage colony-stimulating factor (GM-CSF) potentiates viral production yet enhances the antiviral effect mediated by 3'-azido-2'3'-dideoxythymidine (AZT) and other dideoxynucleoside congeners of thymidine.

Perno, C F; Yarchoan, R; Cooney, D A; Hartman, N R; Webb, D S; Hao, Z; Mitsuya, H; Johns, D G; Broder, S

Perno, C F; Yarchoan, R; Cooney, D A; Hartman, N R; Webb, D S; Hao, Z; Mitsuya, H; Johns, D G; Broder, S.

Affiliation

Perno CF; Clinical Oncology Program, National Cancer Institute, Bethesda, Maryland 20892.

J Exp Med ; 169(3): 933-51, 1989 Mar 01.

Article in En | MEDLINE | ID: mdl-2538549

Subject(s)

Colony-Stimulating Factors/pharmacology; Dideoxynucleosides/pharmacology; Growth Substances/pharmacology; HIV-1/physiology; Monocytes/microbiology; Zidovudine/pharmacology; Cells, Cultured; Granulocyte-Macrophage Colony-Stimulating Factor; HIV-1/drug effects; Humans; Lymphocytes/microbiology; Stavudine; Virus Replication/drug effects; Zidovudine/analogs & derivatives

Fulltext

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Monocytes / Dideoxynucleosides / Zidovudine / Colony-Stimulating Factors / HIV-1 / Growth Substances Limits: Humans Language: En Journal: J Exp Med Year: 1989 Type: Article

Fulltext

XML

PubMed Links

Search on Google