A population model of early rheumatoid arthritis disease activity during treatment with methotrexate, sulfasalazine and hydroxychloroquine.

Wojciechowski, Jessica; Wiese, Michael D; Proudman, Susanna M; Foster, David J R; Upton, Richard N

Wojciechowski, Jessica; Wiese, Michael D; Proudman, Susanna M; Foster, David J R; Upton, Richard N.

Affiliation

Wojciechowski J; Australian Centre for Pharmacometrics, University of South Australia, Adelaide, Australia.

Br J Clin Pharmacol ; 79(5): 777-88, 2015 May.

Article in En | MEDLINE | ID: mdl-25394211

Subject(s)

Antirheumatic Agents/therapeutic use; Arthritis, Rheumatoid/drug therapy; Hydroxychloroquine/therapeutic use; Methotrexate/therapeutic use; Models, Biological; Sulfasalazine/therapeutic use; Adolescent; Adult; Aged; Aged, 80 and over; Antirheumatic Agents/administration & dosage; Arthritis, Rheumatoid/pathology; Bayes Theorem; Data Interpretation, Statistical; Disease Progression; Drug Therapy, Combination; Female; Humans; Hydroxychloroquine/administration & dosage; Joints/pathology; Male; Methotrexate/administration & dosage; Middle Aged; Predictive Value of Tests; Severity of Illness Index; Sulfasalazine/administration & dosage; Time Factors; Treatment Outcome; Young Adult

Key words

28 Joint Disease Activity Score; disease activity; disease modifying anti-rheumatic drugs; population modelling; rheumatoid arthritis

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Arthritis, Rheumatoid / Sulfasalazine / Methotrexate / Antirheumatic Agents / Hydroxychloroquine / Models, Biological Type of study: Prognostic_studies Limits: Adolescent / Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Language: En Journal: Br J Clin Pharmacol Year: 2015 Type: Article Affiliation country: Australia

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