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Mechanistic studies of cancer cell mitochondria- and NQO1-mediated redox activation of beta-lapachone, a potentially novel anticancer agent.
Li, Jason Z; Ke, Yuebin; Misra, Hara P; Trush, Michael A; Li, Y Robert; Zhu, Hong; Jia, Zhenquan.
Affiliation
  • Li JZ; Virginia Tech CRC, Blacksburg, VA, USA.
  • Ke Y; Shenzhen Center for Disease Control and Prevention, Shenzhen 518055, China.
  • Misra HP; Virginia Tech CRC, Blacksburg, VA, USA.
  • Trush MA; Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD, USA.
  • Li YR; Campbell University School of Osteopathic Medicine, Buies Creek, NC, USA; Virginia Tech-Wake Forest University SBES, Blacksburg, VA, USA; Department of Biology, University of North Carolina at Greensboro, NC, USA.
  • Zhu H; Campbell University School of Osteopathic Medicine, Buies Creek, NC, USA. Electronic address: zhu@campbell.edu.
  • Jia Z; Department of Biology, University of North Carolina at Greensboro, NC, USA. Electronic address: z_jia@uncg.edu.
Toxicol Appl Pharmacol ; 281(3): 285-93, 2014 Dec 15.
Article in En | MEDLINE | ID: mdl-25448047
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Prodrugs / Naphthoquinones / NAD(P)H Dehydrogenase (Quinone) / Electron Transport Complex I / Neoplasm Proteins / Neoplasms / Antineoplastic Agents, Phytogenic Limits: Animals / Humans Language: En Journal: Toxicol Appl Pharmacol Year: 2014 Type: Article Affiliation country: United States
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Prodrugs / Naphthoquinones / NAD(P)H Dehydrogenase (Quinone) / Electron Transport Complex I / Neoplasm Proteins / Neoplasms / Antineoplastic Agents, Phytogenic Limits: Animals / Humans Language: En Journal: Toxicol Appl Pharmacol Year: 2014 Type: Article Affiliation country: United States