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Wnt5a and Wnt11 inhibit the canonical Wnt pathway and promote cardiac progenitor development via the Caspase-dependent degradation of AKT.
Bisson, Joseph A; Mills, Bradley; Paul Helt, Jay-Christian; Zwaka, Thomas P; Cohen, Ethan David.
Affiliation
  • Bisson JA; Division of Endocrinology and Metabolism, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA; Aab Cardiovascular Research Institute, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA.
  • Mills B; Division of Endocrinology and Metabolism, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA; Aab Cardiovascular Research Institute, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA.
  • Paul Helt JC; Division of Endocrinology and Metabolism, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA; Aab Cardiovascular Research Institute, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA.
  • Zwaka TP; Black Family Stem Cell Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Department of Developmental and Regenerative Medicine, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
  • Cohen ED; Division of Endocrinology and Metabolism, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA; Aab Cardiovascular Research Institute, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA. Electronic address: Ethan_Cohen@URMC.Rochester.edu.
Dev Biol ; 398(1): 80-96, 2015 Feb 01.
Article in En | MEDLINE | ID: mdl-25482987
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Stem Cells / Gene Expression Regulation, Developmental / Proto-Oncogene Proteins c-akt / Wnt Proteins / Wnt Signaling Pathway / Heart Limits: Animals / Pregnancy Language: En Journal: Dev Biol Year: 2015 Type: Article Affiliation country: United States
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Stem Cells / Gene Expression Regulation, Developmental / Proto-Oncogene Proteins c-akt / Wnt Proteins / Wnt Signaling Pathway / Heart Limits: Animals / Pregnancy Language: En Journal: Dev Biol Year: 2015 Type: Article Affiliation country: United States