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PKR downregulation prevents neurodegeneration and ß-amyloid production in a thiamine-deficient model.
Mouton-Liger, F; Rebillat, A-S; Gourmaud, S; Paquet, C; Leguen, A; Dumurgier, J; Bernadelli, P; Taupin, V; Pradier, L; Rooney, T; Hugon, J.
Affiliation
  • Mouton-Liger F; 1] Inserm UMR-S942, Paris 75010, France [2] Department of Histology, Pathology and Biochemistry, Saint Louis Lariboisière Fernand Hospital, Service AP-HP, University of Paris Diderot, Paris, France.
  • Rebillat AS; Inserm UMR-S942, Paris 75010, France.
  • Gourmaud S; 1] Inserm UMR-S942, Paris 75010, France [2] Department of Histology, Pathology and Biochemistry, Saint Louis Lariboisière Fernand Hospital, Service AP-HP, University of Paris Diderot, Paris, France.
  • Paquet C; 1] Inserm UMR-S942, Paris 75010, France [2] Department of Histology, Pathology and Biochemistry, Saint Louis Lariboisière Fernand Hospital, Service AP-HP, University of Paris Diderot, Paris, France [3] Clinical and Research Memory Center, Paris Nord Ile de France Saint Louis Lariboisière Fernand Hos
  • Leguen A; Inserm UMR-S942, Paris 75010, France.
  • Dumurgier J; 1] Department of Histology, Pathology and Biochemistry, Saint Louis Lariboisière Fernand Hospital, Service AP-HP, University of Paris Diderot, Paris, France [2] Clinical and Research Memory Center, Paris Nord Ile de France Saint Louis Lariboisière Fernand Hospital, AP-HP, University of Paris Diderot
  • Bernadelli P; Sanofi-Aventis Therapeutic Strategy Unit Aging, Chilly-Mazarin, France.
  • Taupin V; Sanofi-Aventis Therapeutic Strategy Unit Aging, Chilly-Mazarin, France.
  • Pradier L; Sanofi-Aventis Therapeutic Strategy Unit Aging, Chilly-Mazarin, France.
  • Rooney T; Sanofi-Aventis Therapeutic Strategy Unit Aging, Chilly-Mazarin, France.
  • Hugon J; 1] Inserm UMR-S942, Paris 75010, France [2] Department of Histology, Pathology and Biochemistry, Saint Louis Lariboisière Fernand Hospital, Service AP-HP, University of Paris Diderot, Paris, France [3] Clinical and Research Memory Center, Paris Nord Ile de France Saint Louis Lariboisière Fernand Hos
Cell Death Dis ; 6: e1594, 2015 Jan 15.
Article in En | MEDLINE | ID: mdl-25590804
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Thiamine / Down-Regulation / Amyloid beta-Peptides / EIF-2 Kinase / Nerve Degeneration Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Cell Death Dis Year: 2015 Type: Article Affiliation country: France
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Thiamine / Down-Regulation / Amyloid beta-Peptides / EIF-2 Kinase / Nerve Degeneration Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Cell Death Dis Year: 2015 Type: Article Affiliation country: France