Nanoparticulate Impurities in Pharmaceutical-Grade Sugars and their Interference with Light Scattering-Based Analysis of Protein Formulations.

Weinbuch, Daniel; Cheung, Jason K; Ketelaars, Jurgen; Filipe, Vasco; Hawe, Andrea; den Engelsman, John; Jiskoot, Wim

Weinbuch, Daniel; Cheung, Jason K; Ketelaars, Jurgen; Filipe, Vasco; Hawe, Andrea; den Engelsman, John; Jiskoot, Wim.

Affiliation

Weinbuch D; Coriolis Pharma, Am Klopferspitz 19, 82152, Martinsried-Munich, Germany.

Pharm Res ; 32(7): 2419-27, 2015 Jul.

Article in En | MEDLINE | ID: mdl-25630820

Subject(s)

Biopharmaceutics/methods; Carbohydrates/chemistry; Drug Contamination; Dynamic Light Scattering; Muramidase/analysis; Nanoparticles/analysis; Biopharmaceutics/standards; Chemistry, Pharmaceutical; Drug Contamination/prevention & control; Microscopy, Electron, Scanning; Spectrometry, Fluorescence; Spectroscopy, Fourier Transform Infrared; Ultrafiltration

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Biopharmaceutics / Carbohydrates / Muramidase / Drug Contamination / Nanoparticles / Dynamic Light Scattering Type of study: Prognostic_studies Language: En Journal: Pharm Res Year: 2015 Type: Article Affiliation country: Germany

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