Reductions in kinesin expression are associated with nitric oxide-induced axonal damage.

Redondo, Juliana; Hares, Kelly; Wilkins, Alastair; Scolding, Neil; Kemp, Kevin

Redondo, Juliana; Hares, Kelly; Wilkins, Alastair; Scolding, Neil; Kemp, Kevin.

Affiliation

Redondo J; Multiple Sclerosis and Stem Cell Group, School of Clinical Sciences, University of Bristol, Bristol, United Kingdom.

J Neurosci Res ; 93(6): 882-92, 2015 Jun.

Article in En | MEDLINE | ID: mdl-25639260

Subject(s)

Axons/pathology; Free Radical Scavengers/toxicity; Gene Expression Regulation/drug effects; Kinesins/metabolism; Neurons/drug effects; Nitric Oxide/toxicity; Analysis of Variance; Animals; Antigens, CD/metabolism; Axons/drug effects; Bone Marrow Cells/drug effects; Cell Survival/drug effects; Cells, Cultured; Cerebral Cortex/cytology; Coculture Techniques; Embryo, Mammalian; Humans; Kinesins/genetics; Neurofilament Proteins/metabolism; Rats; Time Factors

Key words

axonal transport; mesenchymal stem cells; motor proteins; neuroprotection; nitrosative stress

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Axons / Gene Expression Regulation / Free Radical Scavengers / Kinesins / Neurons / Nitric Oxide Type of study: Risk_factors_studies Limits: Animals / Humans Language: En Journal: J Neurosci Res Year: 2015 Type: Article Affiliation country: United kingdom

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