Inhibition of protein synthesis leading to unfolded protein response is the major event in abrin-mediated apoptosis.

Mishra, Ritu; Kumar, Meenakshi Sundaram; Karande, Anjali A

Mishra, Ritu; Kumar, Meenakshi Sundaram; Karande, Anjali A.

Affiliation

Mishra R; Department of Biochemistry, Indian Institute of Science, Bangalore, 560012, Karnataka, India.

Mol Cell Biochem ; 403(1-2): 255-65, 2015 May.

Article in En | MEDLINE | ID: mdl-25753921

Subject(s)

Abrin/pharmacology; Apoptosis/drug effects; Protein Biosynthesis/drug effects; Unfolded Protein Response/drug effects; Abrin/isolation & purification; Caspase 3/metabolism; Chromatography, Affinity; Endocytosis/drug effects; Escherichia coli/metabolism; Humans; Jurkat Cells; Kinetics; Mutant Proteins/toxicity; Protein Structure, Secondary; Ricin/chemistry; Ricin/isolation & purification; p38 Mitogen-Activated Protein Kinases/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Protein Biosynthesis / Apoptosis / Abrin / Unfolded Protein Response Limits: Humans Language: En Journal: Mol Cell Biochem Year: 2015 Type: Article Affiliation country: India

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