Antioxidant icariside II combined with insulin restores erectile function in streptozotocin-induced type 1 diabetic rats.

Wang, Lin; Xu, Yongde; Li, Huixi; Lei, Hongen; Guan, Ruili; Gao, Zhezhu; Xin, Zhongcheng

Wang, Lin; Xu, Yongde; Li, Huixi; Lei, Hongen; Guan, Ruili; Gao, Zhezhu; Xin, Zhongcheng.

Affiliation

Wang L; Andrology Center, Peking University First Hospital, Peking University, Beijing, China.

J Cell Mol Med ; 19(5): 960-9, 2015 May.

Article in En | MEDLINE | ID: mdl-25781208

Subject(s)

Antioxidants/pharmacology; Diabetes Mellitus, Experimental/prevention & control; Diabetes Mellitus, Type 1/prevention & control; Flavonoids/pharmacology; Insulin/pharmacology; Penile Erection/drug effects; Animals; Blood Pressure/drug effects; Blotting, Western; Diabetes Mellitus, Experimental/blood; Diabetes Mellitus, Experimental/physiopathology; Diabetes Mellitus, Type 1/blood; Diabetes Mellitus, Type 1/physiopathology; Drug Synergism; Drugs, Chinese Herbal/pharmacology; Erectile Dysfunction/metabolism; Erectile Dysfunction/physiopathology; Erectile Dysfunction/prevention & control; Fluorescent Antibody Technique; Glycation End Products, Advanced/antagonists & inhibitors; Glycation End Products, Advanced/metabolism; Hypoglycemic Agents/pharmacology; Male; Nitric Oxide Synthase/metabolism; Oxidative Stress/drug effects; Penile Erection/physiology; Random Allocation; Rats, Sprague-Dawley; Receptor for Advanced Glycation End Products/antagonists & inhibitors; Receptor for Advanced Glycation End Products/metabolism

Key words

diabetes mellitus; erectile dysfunction; icariside II; metabolic memory

Fulltext

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Flavonoids / Penile Erection / Diabetes Mellitus, Experimental / Diabetes Mellitus, Type 1 / Insulin / Antioxidants Limits: Animals Language: En Journal: J Cell Mol Med Journal subject: BIOLOGIA MOLECULAR Year: 2015 Type: Article Affiliation country: China

Fulltext

XML

PubMed Links

Search on Google