Pregnant rats treated with a high-fat/prooxidant Western diet with ANG II and TNF-&#945; are resistant to elevations in blood pressure and renal oxidative stress.

Cunningham, Mark W; West, Crystal A; Wen, Xuerong; Deng, Aihua; Baylis, Chris

Pregnant rats treated with a high-fat/prooxidant Western diet with ANG II and TNF-α are resistant to elevations in blood pressure and renal oxidative stress.

Cunningham, Mark W; West, Crystal A; Wen, Xuerong; Deng, Aihua; Baylis, Chris.

Affiliation

Cunningham MW; Department of Pharmacology and Toxicology, University of Mississippi Medical Center, Jackson, Mississippi; Mwcunningham@umc.edu.
West CA; Department of Physiology and Functional Genomics, Department of Medicine, University of Florida College of Medicine, Gainesville, Florida; and.
Wen X; Division of Nephrology, Hypertension and Renal Transplantation, Department of Medicine, University of Florida College of Medicine, Gainesville, Florida.
Deng A; Department of Physiology and Functional Genomics, Department of Medicine, University of Florida College of Medicine, Gainesville, Florida; and.
Baylis C; Department of Physiology and Functional Genomics, Department of Medicine, University of Florida College of Medicine, Gainesville, Florida; and Division of Nephrology, Hypertension and Renal Transplantation, Department of Medicine, University of Florida College of Medicine, Gainesville, Florida.

Am J Physiol Regul Integr Comp Physiol ; 308(11): R945-56, 2015 Jun 01.

Article in En | MEDLINE | ID: mdl-25810384

Subject(s)

Angiotensin II; Arterial Pressure; Diet, High-Fat; Diet, Western; Hypertension/prevention & control; Kidney Cortex/metabolism; Oxidative Stress; Tumor Necrosis Factor-alpha; Animals; Antioxidants/metabolism; Aorta/metabolism; Aorta/physiopathology; Birth Weight; Disease Models, Animal; Female; Hypertension/etiology; Hypertension/metabolism; Hypertension/physiopathology; Litter Size; Nitric Oxide/metabolism; Pregnancy; Rats, Sprague-Dawley; Telemetry; Time Factors

Key words

ANG II; Western diet; nitric oxide; oxidative stress; tumor necrosis factor-α

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Angiotensin II / Tumor Necrosis Factor-alpha / Oxidative Stress / Diet, High-Fat / Arterial Pressure / Diet, Western / Hypertension / Kidney Cortex Type of study: Etiology_studies / Prognostic_studies / Risk_factors_studies Limits: Animals / Pregnancy Language: En Journal: Am J Physiol Regul Integr Comp Physiol Journal subject: FISIOLOGIA Year: 2015 Type: Article

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