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Depletion of SIRT6 causes cellular senescence, DNA damage, and telomere dysfunction in human chondrocytes.
Nagai, K; Matsushita, T; Matsuzaki, T; Takayama, K; Matsumoto, T; Kuroda, R; Kurosaka, M.
Affiliation
  • Nagai K; Department of Orthopaedic Surgery, Kobe University Graduate School of Medicine, 7-5-1, Kusunoki-cho, Chuo-ku, Kobe, 650-0017, Japan. Electronic address: kant_kantona@yahoo.co.jp.
  • Matsushita T; Department of Orthopaedic Surgery, Kobe University Graduate School of Medicine, 7-5-1, Kusunoki-cho, Chuo-ku, Kobe, 650-0017, Japan. Electronic address: matsushi@kobe-u.ac.jp.
  • Matsuzaki T; Department of Orthopaedic Surgery, Kobe University Graduate School of Medicine, 7-5-1, Kusunoki-cho, Chuo-ku, Kobe, 650-0017, Japan. Electronic address: tokiomatsuzaki@yahoo.co.jp.
  • Takayama K; Department of Orthopaedic Surgery, Kobe University Graduate School of Medicine, 7-5-1, Kusunoki-cho, Chuo-ku, Kobe, 650-0017, Japan. Electronic address: kojitakayama1978@gmail.com.
  • Matsumoto T; Department of Orthopaedic Surgery, Kobe University Graduate School of Medicine, 7-5-1, Kusunoki-cho, Chuo-ku, Kobe, 650-0017, Japan. Electronic address: matsun@m4.dion.ne.jp.
  • Kuroda R; Department of Orthopaedic Surgery, Kobe University Graduate School of Medicine, 7-5-1, Kusunoki-cho, Chuo-ku, Kobe, 650-0017, Japan. Electronic address: kurodar@med.kobe-u.ac.jp.
  • Kurosaka M; Department of Orthopaedic Surgery, Kobe University Graduate School of Medicine, 7-5-1, Kusunoki-cho, Chuo-ku, Kobe, 650-0017, Japan. Electronic address: kurosaka@med.kobe-u.ac.jp.
Osteoarthritis Cartilage ; 23(8): 1412-20, 2015 Aug.
Article in En | MEDLINE | ID: mdl-25819580
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: DNA Damage / Telomere / Cellular Senescence / Chondrocytes / Sirtuins Type of study: Etiology_studies Limits: Humans Language: En Journal: Osteoarthritis Cartilage Journal subject: ORTOPEDIA / REUMATOLOGIA Year: 2015 Type: Article
Fulltext
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: DNA Damage / Telomere / Cellular Senescence / Chondrocytes / Sirtuins Type of study: Etiology_studies Limits: Humans Language: En Journal: Osteoarthritis Cartilage Journal subject: ORTOPEDIA / REUMATOLOGIA Year: 2015 Type: Article