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Identification of novel therapeutic targets in acute leukemias with NRAS mutations using a pharmacologic approach.
Nonami, Atsushi; Sattler, Martin; Weisberg, Ellen; Liu, Qingsong; Zhang, Jianming; Patricelli, Matthew P; Christie, Amanda L; Saur, Amy M; Kohl, Nancy E; Kung, Andrew L; Yoon, Hojong; Sim, Taebo; Gray, Nathanael S; Griffin, James D.
Affiliation
  • Nonami A; Department of Medical Oncology and Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA;
  • Sattler M; Department of Medical Oncology and Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA;
  • Weisberg E; Department of Medical Oncology and Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA;
  • Liu Q; Department of Medicine and Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA;
  • Zhang J; Department of Medicine and Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA;
  • Patricelli MP; ActivX Biosciences, Inc., La Jolla, CA;
  • Christie AL; Lurie Family Imaging Center, Dana-Farber Cancer Institute, MA;
  • Saur AM; Lurie Family Imaging Center, Dana-Farber Cancer Institute, MA;
  • Kohl NE; Lurie Family Imaging Center, Dana-Farber Cancer Institute, MA;
  • Kung AL; Lurie Family Imaging Center, Dana-Farber Cancer Institute, MA;
  • Yoon H; Chemical Kinomics Research Center, Korea Institute of Science and Technology, Seoul, Korea; and.
  • Sim T; Chemical Kinomics Research Center, Korea Institute of Science and Technology, Seoul, Korea; and KU-KIST Graduate School of Converging Science and Technology, Seongbuk-gu, Seoul, Korea.
  • Gray NS; Department of Medicine and Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA;
  • Griffin JD; Department of Medical Oncology and Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA;
Blood ; 125(20): 3133-43, 2015 May 14.
Article in En | MEDLINE | ID: mdl-25833960

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Leukemia / GTP Phosphohydrolases / Membrane Proteins / Mutation Type of study: Diagnostic_studies Limits: Animals / Humans Language: En Journal: Blood Year: 2015 Type: Article

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Leukemia / GTP Phosphohydrolases / Membrane Proteins / Mutation Type of study: Diagnostic_studies Limits: Animals / Humans Language: En Journal: Blood Year: 2015 Type: Article