Podocyte hypertrophy precedes apoptosis under experimental diabetic conditions.

Lee, Sun Ha; Moon, Sung Jin; Paeng, Jisun; Kang, Hye-Young; Nam, Bo Young; Kim, Seonghun; Kim, Chan Ho; Lee, Mi Jung; Oh, Hyung Jung; Park, Jung Tak; Han, Seung Hyeok; Yoo, Tae-Hyun; Kang, Shin-Wook

Lee, Sun Ha; Moon, Sung Jin; Paeng, Jisun; Kang, Hye-Young; Nam, Bo Young; Kim, Seonghun; Kim, Chan Ho; Lee, Mi Jung; Oh, Hyung Jung; Park, Jung Tak; Han, Seung Hyeok; Yoo, Tae-Hyun; Kang, Shin-Wook.

Affiliation

Lee SH; Department of Internal Medicine, College of Medicine, Brain Korea 21 for Medical Science, Severance Biomedical Science Institute, Yonsei University, 134 Shinchon-Dong Seodaemoon-Gu, Seoul, 120-752, Korea.

Apoptosis ; 20(8): 1056-71, 2015 Aug.

Article in En | MEDLINE | ID: mdl-25953318

Subject(s)

Apoptosis/drug effects; Diabetes Mellitus, Experimental/chemically induced; Podocytes/pathology; Animals; Apoptosis Regulatory Proteins/metabolism; Aspartic Acid/analogs & derivatives; Aspartic Acid/pharmacology; Caspase 3/metabolism; Caspase Inhibitors/pharmacology; Cells, Cultured; ErbB Receptors/antagonists & inhibitors; ErbB Receptors/metabolism; Gene Expression/drug effects; Hypertrophy/metabolism; Hypertrophy/pathology; Kidney Glomerulus/drug effects; Kidney Glomerulus/metabolism; Kidney Glomerulus/pathology; Male; Mice; Podocytes/drug effects; Podocytes/metabolism; Protein Kinase Inhibitors/pharmacology; Pyrimidines/pharmacology; Pyrroles/pharmacology; Rats, Sprague-Dawley; Streptozocin

Fulltext

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Apoptosis / Diabetes Mellitus, Experimental / Podocytes Limits: Animals Language: En Journal: Apoptosis Year: 2015 Type: Article

Fulltext

XML

PubMed Links

Search on Google